CLINICAL TRIALS PROFILE FOR TAGAMET HYDROCHLORIDE IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER

All Clinical Trials for Tagamet Hydrochloride In Sodium Chloride 0.9% In Plastic Container

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00038402 ↗	Evaluation of the Addition of Herceptin to Standard Chemotherapy in the Neoadjuvant Setting for Operable Breast Cancer	Completed	Genentech, Inc.	Phase 3	2001-04-01	The purpose of this study is to evaluate the addition of Herceptin to standard chemotherapy treatment of patients newly diagnosed with operable breast cancer. Other objectives: 1) to evaluate the potential of this therapy to reduce the size of the tumor and increase the possibility of breast conservative surgery, 2) evaluate the ability of this regimen to prevent recurrence of breast cancer and impact on survival, 3) determine side effect profile with the addition of Herceptin, and 4) evaluate significance of HER2 expression by two different methods.
NCT00038402 ↗	Evaluation of the Addition of Herceptin to Standard Chemotherapy in the Neoadjuvant Setting for Operable Breast Cancer	Completed	M.D. Anderson Cancer Center	Phase 3	2001-04-01	The purpose of this study is to evaluate the addition of Herceptin to standard chemotherapy treatment of patients newly diagnosed with operable breast cancer. Other objectives: 1) to evaluate the potential of this therapy to reduce the size of the tumor and increase the possibility of breast conservative surgery, 2) evaluate the ability of this regimen to prevent recurrence of breast cancer and impact on survival, 3) determine side effect profile with the addition of Herceptin, and 4) evaluate significance of HER2 expression by two different methods.
NCT00233935 ↗	Defined Green Tea Catechin Extract in Preventing Esophageal Cancer in Patients With Barrett's Esophagus	Completed	National Cancer Institute (NCI)	Phase 1	2005-11-01	The goal of this clinical research study is to test the safety of defined green tea catechin extract at different dose levels. Researchers also want to find out what effects, good and bad, it may have on individual and their risk for esophagus cancer. Esophagus cancer is an increased risk associated with Barrett's esophagus. Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of defined green tea catechin extract may prevent esophageal cancer.
NCT01256879 ↗	Cimetidine Biowaivers	Completed	Food and Drug Administration (FDA)	Phase 4	2011-03-01	The purpose of this research is to see if non-drug ingredients in capsules and oral solutions affect how well drugs are absorbed. This is called "bioequivalence." Medications taken by mouth, such as capsules and solutions, need to be absorbed into the body in order to do any good. Capsules and solutions contain a drug, but also contain non-drug ingredients that are called excipients or fillers. Excipients in the capsules and solutions can impact how much drug is absorbed into the body. This is called "bioINequivalence." Capsules and solutions in this research contain the drug cimetidine. This drug is being used since it has high water solubility (can dissolve in water) and low ability to be absorbed.
NCT01256879 ↗	Cimetidine Biowaivers	Completed	University of Maryland	Phase 4	2011-03-01	The purpose of this research is to see if non-drug ingredients in capsules and oral solutions affect how well drugs are absorbed. This is called "bioequivalence." Medications taken by mouth, such as capsules and solutions, need to be absorbed into the body in order to do any good. Capsules and solutions contain a drug, but also contain non-drug ingredients that are called excipients or fillers. Excipients in the capsules and solutions can impact how much drug is absorbed into the body. This is called "bioINequivalence." Capsules and solutions in this research contain the drug cimetidine. This drug is being used since it has high water solubility (can dissolve in water) and low ability to be absorbed.
NCT01256879 ↗	Cimetidine Biowaivers	Completed	University of Maryland, Baltimore	Phase 4	2011-03-01	The purpose of this research is to see if non-drug ingredients in capsules and oral solutions affect how well drugs are absorbed. This is called "bioequivalence." Medications taken by mouth, such as capsules and solutions, need to be absorbed into the body in order to do any good. Capsules and solutions contain a drug, but also contain non-drug ingredients that are called excipients or fillers. Excipients in the capsules and solutions can impact how much drug is absorbed into the body. This is called "bioINequivalence." Capsules and solutions in this research contain the drug cimetidine. This drug is being used since it has high water solubility (can dissolve in water) and low ability to be absorbed.
NCT02157376 ↗	Stress Ulcer Prophylaxis of Intravenous Esomeprazole in Chinese Seriously Ill Patients	Completed	AstraZeneca	Phase 3	2014-07-01	The efficacy of esomeprazole will be compared versus cimetidine (a drug that previously demonstrated prevention of bleeding events) during treatment period in proportion of patients for the prevention of upper GI bleeding.

Clinical Trial Conditions for Tagamet Hydrochloride In Sodium Chloride 0.9% In Plastic Container

Condition Name

Condition Name for Tagamet Hydrochloride In Sodium Chloride 0.9% In Plastic Container
Intervention	Trials
Endogenous Biomarkers	1
Prognostic Stage IIIA Breast Cancer AJCC v8	1
Anatomic Stage IIA Breast Cancer AJCC v8	1
Healthy	1

Condition MeSH

Condition MeSH for Tagamet Hydrochloride In Sodium Chloride 0.9% In Plastic Container
Intervention	Trials
Breast Neoplasms	2
Breast Carcinoma In Situ	1
Ulcer	1
Barrett Esophagus	1

Clinical Trial Locations for Tagamet Hydrochloride In Sodium Chloride 0.9% In Plastic Container

Trials by Country

Trials by Country for Tagamet Hydrochloride In Sodium Chloride 0.9% In Plastic Container
Location	Trials
United States	6
China	1

Trials by US State

Trials by US State for Tagamet Hydrochloride In Sodium Chloride 0.9% In Plastic Container
Location	Trials
Texas	2
Washington	1
Ohio	1
Maryland	1
New York	1

Clinical Trial Progress for Tagamet Hydrochloride In Sodium Chloride 0.9% In Plastic Container

Clinical Trial Phase

Clinical Trial Phase for Tagamet Hydrochloride In Sodium Chloride 0.9% In Plastic Container
Clinical Trial Phase	Trials
Phase 4	1
Phase 3	2
Phase 2/Phase 3	1

Clinical Trial Status

Clinical Trial Status for Tagamet Hydrochloride In Sodium Chloride 0.9% In Plastic Container
Clinical Trial Phase	Trials
Completed	4
Recruiting	2

Clinical Trial Sponsors for Tagamet Hydrochloride In Sodium Chloride 0.9% In Plastic Container

Sponsor Name

Sponsor Name for Tagamet Hydrochloride In Sodium Chloride 0.9% In Plastic Container
Sponsor	Trials
Food and Drug Administration (FDA)	1
University of Maryland	1
University of Maryland, Baltimore	1

Sponsor Type

Sponsor Type for Tagamet Hydrochloride In Sodium Chloride 0.9% In Plastic Container
Sponsor	Trials
Other	5
NIH	3
Industry	2