Evaluation of the Addition of Herceptin to Standard Chemotherapy in the Neoadjuvant Setting for Operable Breast Cancer
Completed
Genentech, Inc.
Phase 3
2001-04-01
The purpose of this study is to evaluate the addition of Herceptin to standard chemotherapy
treatment of patients newly diagnosed with operable breast cancer.
Other objectives: 1) to evaluate the potential of this therapy to reduce the size of the
tumor and increase the possibility of breast conservative surgery, 2) evaluate the ability of
this regimen to prevent recurrence of breast cancer and impact on survival, 3) determine side
effect profile with the addition of Herceptin, and 4) evaluate significance of HER2
expression by two different methods.
Evaluation of the Addition of Herceptin to Standard Chemotherapy in the Neoadjuvant Setting for Operable Breast Cancer
Completed
M.D. Anderson Cancer Center
Phase 3
2001-04-01
The purpose of this study is to evaluate the addition of Herceptin to standard chemotherapy
treatment of patients newly diagnosed with operable breast cancer.
Other objectives: 1) to evaluate the potential of this therapy to reduce the size of the
tumor and increase the possibility of breast conservative surgery, 2) evaluate the ability of
this regimen to prevent recurrence of breast cancer and impact on survival, 3) determine side
effect profile with the addition of Herceptin, and 4) evaluate significance of HER2
expression by two different methods.
Defined Green Tea Catechin Extract in Preventing Esophageal Cancer in Patients With Barrett's Esophagus
Completed
National Cancer Institute (NCI)
Phase 1
2005-11-01
The goal of this clinical research study is to test the safety of defined green tea catechin
extract at different dose levels. Researchers also want to find out what effects, good and
bad, it may have on individual and their risk for esophagus cancer. Esophagus cancer is an
increased risk associated with Barrett's esophagus. Chemoprevention is the use of certain
drugs to keep cancer from forming, growing, or coming back. The use of defined green tea
catechin extract may prevent esophageal cancer.
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