Safety and Efficacy of Tafamidis in Patients With Transthyretin Cardiomyopathy
Active, not recruiting
This Phase 3 study will investigate the efficacy, safety and tolerability of an oral daily
dose of 20 mg or 80 mg tafamidis meglumine capsules compared to placebo in subjects with
either transthyretin genetic variants or wild-type transthyretin resulting in amyloid
Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy
Phase 3 extension study to evaluate the safety of oral daily dosing of 20 mg or 80 mg
tafamidis meglumine in subjects with either transthyretin genetic variants or wild-type
transthyretin resulting in amyloid cardiomyopathy
A Study Comparing Amounts of 2 Different Forms of Tafamidis (PF-6291826) in the Blood.
Not yet recruiting
2 different formulations and doses of tafamidis will be compared. All subjects will receive
both doses/formulations. Subjects will take tafamidis for 7 days, on the first 2 days they
will take tafamidis twice, 12 hours apart and then once a day for the next 5 days. Subjects
will be fasted before taking the drug. Blood samples will be taken to measure the amount of
tafamidis starting on day 7 and ending on day 8. At least 16 days after the first
formulation/dose is given, all subjects will repeat the procedure with the other
Serving leading biopharmaceutical companies globally:
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.