Sulindac and Plant Compounds in Preventing Colon Cancer
Terminated
National Cancer Institute (NCI)
N/A
1996-08-01
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the
development or recurrence of cancer. The use of sulindac may be an effective way to prevent
colon cancer. Eating a diet rich in fruits and vegetables appears to reduce the risk of some
types of cancer. Curcumin, rutin, and quercetin are compounds found in plants that may
prevent the development of colon cancer.
PURPOSE: Randomized clinical trial to study the effectiveness of sulindac, curcumin, rutin,
and quercetin in preventing colon cancer.
Sulindac and Plant Compounds in Preventing Colon Cancer
Terminated
University of Medicine and Dentistry of New Jersey
N/A
1996-08-01
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the
development or recurrence of cancer. The use of sulindac may be an effective way to prevent
colon cancer. Eating a diet rich in fruits and vegetables appears to reduce the risk of some
types of cancer. Curcumin, rutin, and quercetin are compounds found in plants that may
prevent the development of colon cancer.
PURPOSE: Randomized clinical trial to study the effectiveness of sulindac, curcumin, rutin,
and quercetin in preventing colon cancer.
Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon Polyps
Completed
Chao Family Comprehensive Cancer Center
Phase 3
1998-07-01
This randomized phase III trial is studying eflornithine and sulindac to see how well they
work compared to a placebo in preventing colorectal cancer in patients with colon polyps.
Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming
back. The use of eflornithine and sulindac may prevent colorectal cancer. It is not yet known
whether eflornithine and sulindac are more effective than a placebo in preventing colorectal
cancer
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