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Generated: December 14, 2018

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CLINICAL TRIALS PROFILE FOR SULFAMETHOXAZOLE

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Clinical Trials for Sulfamethoxazole

Trial ID Title Status Sponsor Phase Summary
NCT00000640 A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS Completed Glaxo Wellcome Phase 3 To evaluate the effectiveness of two oral treatments for mild to moderate Pneumocystis carinii pneumonia (PCP): dapsone/trimethoprim or clindamycin/primaquine as compared to a standard treatment program of sulfamethoxazole/trimethoprim (SMX/TMP) to assess the tolerance of these two alternative treatments as compared to the standard treatment of SMX/TMP. Per 09/09/92 amendment, to assess the efficacy and tolerance of these two alternative treatments in patients who are intolerant to SMX/TMP. The type of treatment being studied has the advantages of wide applicability throughout the world (including developing countries) and low cost. An oral treatment is more accessible to patients than drugs given by injection or by inhalation.
NCT00000640 A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS Completed Jacobus Pharmaceutical Phase 3 To evaluate the effectiveness of two oral treatments for mild to moderate Pneumocystis carinii pneumonia (PCP): dapsone/trimethoprim or clindamycin/primaquine as compared to a standard treatment program of sulfamethoxazole/trimethoprim (SMX/TMP) to assess the tolerance of these two alternative treatments as compared to the standard treatment of SMX/TMP. Per 09/09/92 amendment, to assess the efficacy and tolerance of these two alternative treatments in patients who are intolerant to SMX/TMP. The type of treatment being studied has the advantages of wide applicability throughout the world (including developing countries) and low cost. An oral treatment is more accessible to patients than drugs given by injection or by inhalation.
NCT00000640 A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS Completed National Institute of Allergy and Infectious Diseases (NIAID) Phase 3 To evaluate the effectiveness of two oral treatments for mild to moderate Pneumocystis carinii pneumonia (PCP): dapsone/trimethoprim or clindamycin/primaquine as compared to a standard treatment program of sulfamethoxazole/trimethoprim (SMX/TMP) to assess the tolerance of these two alternative treatments as compared to the standard treatment of SMX/TMP. Per 09/09/92 amendment, to assess the efficacy and tolerance of these two alternative treatments in patients who are intolerant to SMX/TMP. The type of treatment being studied has the advantages of wide applicability throughout the world (including developing countries) and low cost. An oral treatment is more accessible to patients than drugs given by injection or by inhalation.
NCT00000655 A Randomized, Double-Blind Study of 566C80 Versus Septra (Sulfamethoxazole/Trimethoprim) for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients Completed Glaxo Wellcome Phase 2 To evaluate the effectiveness of atovaquone (566C80) compared to a standard antipneumocystis agent, (SMX/TMP), for the treatment of mild to moderate Pneumocystis carinii pneumonia (PCP) in AIDS patients. To compare the safety of short-term (21 days) treatment with 566C80 and SMX/TMP in AIDS patients with an acute episode of PCP. Standard therapies for acute treatment of PCP involve either SMX/TMP or pentamidine isetionate. Although both treatments are equally effective, side effects prevent completion of therapy in 11-55 percent of patients.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Sulfamethoxazole

Condition Name

Condition Name for Sulfamethoxazole
Intervention Trials
HIV Infections 36
Pneumonia, Pneumocystis Carinii 27
Leukemia 6
Urinary Tract Infection 6
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Condition MeSH

Condition MeSH for Sulfamethoxazole
Intervention Trials
HIV Infections 38
Pneumonia 32
Pneumonia, Pneumocystis 29
Infection 28
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Clinical Trial Locations for Sulfamethoxazole

Trials by Country

Trials by Country for Sulfamethoxazole
Location Trials
United States 369
Canada 10
Puerto Rico 6
Uganda 5
Switzerland 5
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Trials by US State

Trials by US State for Sulfamethoxazole
Location Trials
California 29
Illinois 23
New York 23
Texas 21
Pennsylvania 16
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Clinical Trial Progress for Sulfamethoxazole

Clinical Trial Phase

Clinical Trial Phase for Sulfamethoxazole
Clinical Trial Phase Trials
Phase 4 20
Phase 3 33
Phase 2/Phase 3 4
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Clinical Trial Status

Clinical Trial Status for Sulfamethoxazole
Clinical Trial Phase Trials
Completed 80
Recruiting 20
Terminated 10
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Clinical Trial Sponsors for Sulfamethoxazole

Sponsor Name

Sponsor Name for Sulfamethoxazole
Sponsor Trials
National Institute of Allergy and Infectious Diseases (NIAID) 29
M.D. Anderson Cancer Center 12
Glaxo Wellcome 8
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Sponsor Type

Sponsor Type for Sulfamethoxazole
Sponsor Trials
Other 141
NIH 50
Industry 39
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Serving hundreds of leading biopharmaceutical companies globally:

US Department of Justice
Colorcon
Queensland Health
Chubb
Accenture
McKesson
Dow
UBS
Teva

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