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Generated: December 11, 2018

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CLINICAL TRIALS PROFILE FOR STIVARGA

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Clinical Trials for Stivarga

Trial ID Title Status Sponsor Phase Summary
NCT01068769 Regorafenib in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor Active, not recruiting Bayer Phase 2 The purpose of this research study is to determine the safety and activity of regorafenib in participants with advanced gastrointestinal stromal tumor (GIST) if the standard approved therapies, imatinib and sunitinib, have failed to control the disease. Regorafenib is a drug that blocks abnormally active signaling enzymes called "tyrosine kinases" which are important to the growth of GIST. This "tyrosine kinase inhibition" is similar to the way that both imatinib and sunitinib work; however, regorafenib blocks certain additional signaling pathways that are not blocked by imatinib or sunitinib. Regorafenib has been not been tested in GIST participants before this research study.
NCT01068769 Regorafenib in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor Active, not recruiting Brigham and Women's Hospital Phase 2 The purpose of this research study is to determine the safety and activity of regorafenib in participants with advanced gastrointestinal stromal tumor (GIST) if the standard approved therapies, imatinib and sunitinib, have failed to control the disease. Regorafenib is a drug that blocks abnormally active signaling enzymes called "tyrosine kinases" which are important to the growth of GIST. This "tyrosine kinase inhibition" is similar to the way that both imatinib and sunitinib work; however, regorafenib blocks certain additional signaling pathways that are not blocked by imatinib or sunitinib. Regorafenib has been not been tested in GIST participants before this research study.
NCT01068769 Regorafenib in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor Active, not recruiting Fox Chase Cancer Center Phase 2 The purpose of this research study is to determine the safety and activity of regorafenib in participants with advanced gastrointestinal stromal tumor (GIST) if the standard approved therapies, imatinib and sunitinib, have failed to control the disease. Regorafenib is a drug that blocks abnormally active signaling enzymes called "tyrosine kinases" which are important to the growth of GIST. This "tyrosine kinase inhibition" is similar to the way that both imatinib and sunitinib work; however, regorafenib blocks certain additional signaling pathways that are not blocked by imatinib or sunitinib. Regorafenib has been not been tested in GIST participants before this research study.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Stivarga

Condition Name

Condition Name for Stivarga
Intervention Trials
Colorectal Neoplasms 6
Colorectal Cancer 4
Metastatic Colorectal Cancer 3
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Condition MeSH

Condition MeSH for Stivarga
Intervention Trials
Colorectal Neoplasms 16
Adenocarcinoma 6
Gastrointestinal Stromal Tumors 6
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Clinical Trial Locations for Stivarga

Trials by Country

Trials by Country for Stivarga
Location Trials
United States 129
Italy 12
France 4
Japan 3
Korea, Republic of 3
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Trials by US State

Trials by US State for Stivarga
Location Trials
North Carolina 9
Florida 8
Ohio 7
Minnesota 7
Massachusetts 7
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Clinical Trial Progress for Stivarga

Clinical Trial Phase

Clinical Trial Phase for Stivarga
Clinical Trial Phase Trials
Phase 3 2
Phase 2 31
Phase 1/Phase 2 2
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Clinical Trial Status

Clinical Trial Status for Stivarga
Clinical Trial Phase Trials
Recruiting 37
Not yet recruiting 4
Active, not recruiting 4
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Clinical Trial Sponsors for Stivarga

Sponsor Name

Sponsor Name for Stivarga
Sponsor Trials
Bayer 25
National Cancer Institute (NCI) 6
Bristol-Myers Squibb 3
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Sponsor Type

Sponsor Type for Stivarga
Sponsor Trials
Other 46
Industry 46
NIH 6
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