Hypertension is one of the most common medical problems in the United States and in the VA
health care system. It has been well-documented that hypertension can be effectively treated.
However, there remain important unresolved clinical questions in the area of antihypertensive
treatment. For example, how much is mortality affected by visit compliance, blood pressure
control and type of antihypertensive agent? Or, are some regimens associated with more
morbidity than others? Or, are there inexpensive regimens that are as effective as more
expensive regimens? The amount of data that is available from this demonstration project
(currently 6,100 patients) will help address these questions. The answers to these questions
should result in better care for veterans with hypertension.
Hypertension is one of the most common medical problems in the United States and in the VA
health care system. It has been well-documented that hypertension can be effectively treated.
However, there remain important unresolved clinical questions in the area of antihypertensive
treatment. For example, how much is mortality affected by visit compliance, blood pressure
control and type of antihypertensive agent? Or, are some regimens associated with more
morbidity than others? Or, are there inexpensive regimens that are as effective as more
expensive regimens? The amount of data that is available from this demonstration project
(currently 6,100 patients) will help address these questions. The answers to these questions
should result in better care for veterans with hypertension.
PHARES Study: Management of Resistant Hypertension
Completed
Assistance Publique - Hôpitaux de Paris
Phase 4
2005-04-01
The purpose of this study is to assess the efficacy of two different treatment regimens for
treating resistant hypertension previously uncontrolled with at least 3 antihypertensive
treatments. The study hypothesis is that these two regimens (one based on increasing
diuretics and the other based on increasing renin angiotensin system blockage) may not differ
in terms of efficacy.
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