Efficacy and Safety Comparison of Tiotropium Inhalation Solution (Respimat Inhaler) and Spiriva HandiHaler in Chronic Obstructive Pulmonary Disease (COPD)
Completed
Boehringer Ingelheim
Phase 3
2002-08-01
Comparison of lung function response between tiotropium inhalation solution and Spiriva
HandiHaler.
A Randomised, Double-blind, Crossover Study of Ba679BR Respimat in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Completed
Boehringer Ingelheim
Phase 2
2006-02-01
The objective of this trial is to compare the efficacy and the safety of Ba 679 BR Respimat 5
ug once daily to tiotropium inhalation capsule 18 ug (Spiriva inhalation capsule) in a
crossover study of 4-week treatment periods in patients with COPD.
Interaction in Chronic Obstructive Pulmonary Disease Experiment
Completed
Radboud University
N/A
2009-09-01
The final purpose of this study is to determine whether bronchodilation and cigarette smoking
in Chronic Obstructive Pulmonary Disease (COPD) patients interact, resulting in an increase
of cardiovascular disease. The aim of this part of the study is to demonstrate the basic
mechanism: Does increased respiratory function after administration of a bronchodilator in
patients with COPD lead to elevated pulmonary retention of the harmful compounds in inhaled
cigarette smoke and to short-term biological effects associated with cardiovascular disease?
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