➤ Get the DrugPatentWatch Daily Briefing

Get Daily Updates on Generic Entry, Litigation, Biosimilars, and more …

Serving leading biopharmaceutical companies globally:

Moodys
Colorcon
Merck
Dow
Mallinckrodt
Boehringer Ingelheim

Last Updated: July 26, 2021

DrugPatentWatch Database Preview

CLINICAL TRIALS PROFILE FOR SODIUM ZIRCONIUM CYCLOSILICATE

➤ Get the DrugPatentWatch Daily Briefing

« Back to Dashboard

All Clinical Trials for Sodium Zirconium Cyclosilicate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT02107092 ↗ Open-label Safety & Efficacy of ZS (Sodium Zirconium Cyclosilicate)10g qd to Extend Study ZS-004 in Hyperkalemia. Completed ZS Pharma, Inc. Phase 3 2014-05-01 Subjects who completed the Double-blind Randomized Maintenance Phase (DBRMP) Study Day 29 visit in ZS-004 (NCT 02088073) and have an i-STAT potassium value that is 3.5 to 6.2 mmol/l inclusive or who discontinued during ZS-004 due to hypo- or hyperkalemia in the DBRMP and have a mean i-STAT potassium value from two consecutive measurements at 0 and 60 minutes on Acute Phase Day 1/Maintenance Phase Day 1 that is 3.5 to 6.2 mmol/l inclusive may have the option to participate in ZS-004E (NCT 021070920). Subjects who discontinued from study ZS-004 due to any other reasons (e.g. adverse events, poor compliance, investigator decision) will not be entered into study ZS-004E. All subjects who continue into the extension study must begin dosing within two (2) days after the last dose of investigational product in ZS-004.
NCT02163499 ↗ Open-label Safety and Efficacy of Sodium Zirconium Cyclosilicate for up to 12 Months Active, not recruiting ZS Pharma, Inc. Phase 3 2014-06-01 The Open-Label Maintenance Study contains an Acute Phase, in which subjects will be dosed with ZS 10 g three times daily (tid) for 24 to 72 hours, followed by a long-term Maintenance Phase.
NCT03127644 ↗ ZS Ph2/3 Dose-response Study in Japan Recruiting AstraZeneca Phase 2/Phase 3 2017-06-14 To assess efficacy of 5 g three times daily (TID) and 10 g TID ZS versus placebo in Japanese patients with hyperkalemia (serum potassium [S-K] ≥ 5.1 mmol/L and ≤ 6.5 mmol/L).
NCT03172702 ↗ Open-label Safety of Sodium Zirconium Cyclosilicate for up to 12 Months in Japanese Subjects With Hyperkalemia Not yet recruiting AstraZeneca Phase 3 2017-07-28 The Open-Label Maintenance Study contains an Correction Phase, in which subjects will be dosed with ZS 10 g three times daily (tid) for 24 to 72 hours, followed by a 12-month long-term Maintenance Phase.
NCT03283267 ↗ A Safety and Pharmacodynamic Study of Healthy Chinese Subjects Administered Sodium Zirconium Cyclosilicate (ZS) Not yet recruiting AstraZeneca Phase 1 2017-10-26 This is a single center, inpatient, open label pharmacodynamic study to determine the effect of 5 g and 10 g doses of Sodium Zirconium Cyclosilicate (ZS) administered once daily (qd) for 4 days on potassium and sodium excretion in healthy Chinese subjects on a standardized, low sodium and high potassium diet.
NCT03303521 ↗ A Study to Test Whether ZS (Sodium Zirconium Cyclosilicate) Can Reduce the Incidence of Increased Blood Potassium Levels Among Dialized Patients. Not yet recruiting AstraZeneca Phase 3 2017-11-09 The purpose of this study is to evaluate the efficacy of ZS in the treatment of hyperkalemia in patients on hemodialysis.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Sodium Zirconium Cyclosilicate

Condition Name

Condition Name for Sodium Zirconium Cyclosilicate
Intervention Trials
Hyperkalemia 12
Hyperkalaemia 4
Heart Failure 2
Heart Failure With Reduced Ejection Fraction 1
[disabled in preview] 0
This preview shows a limited data set
Subscribe for full access, or try a Trial

Condition MeSH

Condition MeSH for Sodium Zirconium Cyclosilicate
Intervention Trials
Hyperkalemia 18
Heart Failure 3
Renal Insufficiency, Chronic 2
Kidney Diseases 2
[disabled in preview] 0
This preview shows a limited data set
Subscribe for full access, or try a Trial

Clinical Trial Locations for Sodium Zirconium Cyclosilicate

Trials by Country

Trials by Country for Sodium Zirconium Cyclosilicate
Location Trials
United States 85
Canada 9
Australia 6
Russian Federation 3
Romania 3
This preview shows a limited data set
Subscribe for full access, or try a Trial

Trials by US State

Trials by US State for Sodium Zirconium Cyclosilicate
Location Trials
Missouri 7
California 7
Texas 6
New York 6
Tennessee 4
This preview shows a limited data set
Subscribe for full access, or try a Trial

Clinical Trial Progress for Sodium Zirconium Cyclosilicate

Clinical Trial Phase

Clinical Trial Phase for Sodium Zirconium Cyclosilicate
Clinical Trial Phase Trials
Phase 4 3
Phase 3 9
Phase 2/Phase 3 1
[disabled in preview] 6
This preview shows a limited data set
Subscribe for full access, or try a Trial

Clinical Trial Status

Clinical Trial Status for Sodium Zirconium Cyclosilicate
Clinical Trial Phase Trials
Not yet recruiting 14
Recruiting 3
Active, not recruiting 1
[disabled in preview] 1
This preview shows a limited data set
Subscribe for full access, or try a Trial

Clinical Trial Sponsors for Sodium Zirconium Cyclosilicate

Sponsor Name

Sponsor Name for Sodium Zirconium Cyclosilicate
Sponsor Trials
AstraZeneca 15
ZS Pharma, Inc. 2
Brigham and Women's Hospital 1
[disabled in preview] 3
This preview shows a limited data set
Subscribe for full access, or try a Trial

Sponsor Type

Sponsor Type for Sodium Zirconium Cyclosilicate
Sponsor Trials
Industry 18
Other 6
[disabled in preview] 0
This preview shows a limited data set
Subscribe for full access, or try a Trial

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

Merck
Moodys
Johnson and Johnson
Medtronic
Baxter
Boehringer Ingelheim

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.