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Generated: December 17, 2018

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CLINICAL TRIALS PROFILE FOR SODIUM PHOSPHATE P 32

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Clinical Trials for Sodium Phosphate P 32

Trial ID Title Status Sponsor Phase Summary
NCT00004767 Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders Completed Johns Hopkins University Phase 2 OBJECTIVES: I. Assess the safety and efficacy of sodium phenylbutyrate, sodium benzoate, sodium phenylacetate, and dietary intervention in patients with urea cycle disorders.
NCT00004767 Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders Completed National Center for Research Resources (NCRR) Phase 2 OBJECTIVES: I. Assess the safety and efficacy of sodium phenylbutyrate, sodium benzoate, sodium phenylacetate, and dietary intervention in patients with urea cycle disorders.
NCT00074165 Treating Patients With Recurrent PCNSL With Carboplatin/BBBD and Adding Rituxan To The Treatment Regimen Terminated National Cancer Institute (NCI) Phase 2 RATIONALE: Monoclonal antibodies, such as rituximab, can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Drugs used in chemotherapy, such as carboplatin, cyclophosphamide, etoposide, etoposide phosphate, and cytarabine, use different ways to stop cancer cells from dividing so they stop growing or die. Osmotic blood-brain barrier disruption uses certain drugs to open the blood vessels around the brain and allow anticancer substances to be delivered directly to the brain tumor. Chemoprotective drugs such as sodium thiosulfate may protect normal cells from the side effects of carboplatin-based chemotherapy. Combining rituximab with chemotherapy given with osmotic blood-brain barrier disruption plus sodium thiosulfate may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combining rituximab with combination chemotherapy given with osmotic blood-brain barrier disruption plus sodium thiosulfate in treating patients who have refractory or recurrent primary CNS lymphoma.
NCT00074165 Treating Patients With Recurrent PCNSL With Carboplatin/BBBD and Adding Rituxan To The Treatment Regimen Terminated OHSU Knight Cancer Institute Phase 2 RATIONALE: Monoclonal antibodies, such as rituximab, can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Drugs used in chemotherapy, such as carboplatin, cyclophosphamide, etoposide, etoposide phosphate, and cytarabine, use different ways to stop cancer cells from dividing so they stop growing or die. Osmotic blood-brain barrier disruption uses certain drugs to open the blood vessels around the brain and allow anticancer substances to be delivered directly to the brain tumor. Chemoprotective drugs such as sodium thiosulfate may protect normal cells from the side effects of carboplatin-based chemotherapy. Combining rituximab with chemotherapy given with osmotic blood-brain barrier disruption plus sodium thiosulfate may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combining rituximab with combination chemotherapy given with osmotic blood-brain barrier disruption plus sodium thiosulfate in treating patients who have refractory or recurrent primary CNS lymphoma.
NCT00075387 Combination Chemotherapy With or Without Sodium Thiosulfate in Preventing Low Platelet Count While Treating Patients With Malignant Brain Tumors Recruiting National Cancer Institute (NCI) Phase 2 This randomized phase II trial studies how well giving combination chemotherapy with or without sodium thiosulfate works in preventing low platelet count while treating patients with malignant brain tumors. Drugs used in chemotherapy, such as carboplatin, cyclophosphamide, and etoposide phosphate, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Sodium thiosulfate may prevent low platelet counts in patients receiving chemotherapy. It is not yet known whether combination chemotherapy is more effective with or without sodium thiosulfate in preventing low platelet count during treatment for brain tumors.
NCT00075387 Combination Chemotherapy With or Without Sodium Thiosulfate in Preventing Low Platelet Count While Treating Patients With Malignant Brain Tumors Recruiting OHSU Knight Cancer Institute Phase 2 This randomized phase II trial studies how well giving combination chemotherapy with or without sodium thiosulfate works in preventing low platelet count while treating patients with malignant brain tumors. Drugs used in chemotherapy, such as carboplatin, cyclophosphamide, and etoposide phosphate, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Sodium thiosulfate may prevent low platelet counts in patients receiving chemotherapy. It is not yet known whether combination chemotherapy is more effective with or without sodium thiosulfate in preventing low platelet count during treatment for brain tumors.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Sodium Phosphate P 32

Condition Name

Condition Name for Sodium Phosphate P 32
Intervention Trials
Colonoscopy 9
Healthy 5
Chronic Kidney Disease 3
Anterior Uveitis 3
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Condition MeSH

Condition MeSH for Sodium Phosphate P 32
Intervention Trials
Iridocyclitis 4
Kidney Diseases 4
Uveitis, Anterior 4
Uveitis 4
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Clinical Trial Locations for Sodium Phosphate P 32

Trials by Country

Trials by Country for Sodium Phosphate P 32
Location Trials
United States 92
Germany 10
Israel 5
France 5
Canada 5
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Trials by US State

Trials by US State for Sodium Phosphate P 32
Location Trials
New York 9
Massachusetts 6
Texas 6
California 5
New Jersey 5
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Clinical Trial Progress for Sodium Phosphate P 32

Clinical Trial Phase

Clinical Trial Phase for Sodium Phosphate P 32
Clinical Trial Phase Trials
Phase 4 27
Phase 3 18
Phase 2/Phase 3 5
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Clinical Trial Status

Clinical Trial Status for Sodium Phosphate P 32
Clinical Trial Phase Trials
Completed 55
Recruiting 22
Not yet recruiting 11
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Clinical Trial Sponsors for Sodium Phosphate P 32

Sponsor Name

Sponsor Name for Sodium Phosphate P 32
Sponsor Trials
National Cancer Institute (NCI) 5
OHSU Knight Cancer Institute 4
Erydel 4
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Sponsor Type

Sponsor Type for Sodium Phosphate P 32
Sponsor Trials
Other 103
Industry 33
NIH 13
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Serving hundreds of leading biopharmaceutical companies globally:

Express Scripts
Cipla
Moodys
UBS
McKesson
Julphar
Cantor Fitzgerald
Queensland Health
US Department of Justice

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