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Last Updated: May 27, 2022

CLINICAL TRIALS PROFILE FOR SODIUM PHENYLBUTYRATE


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All Clinical Trials for Sodium Phenylbutyrate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00002796 ↗ Phase I-II Study of Fluorouracil in Combination With Phenylbutyrate in Advanced Colorectal Cancer Terminated National Cancer Institute (NCI) Phase 1/Phase 2 1997-05-01 Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Interferon-gamma may interfere with the growth of tumor cells and slow the growth of the tumor. Combining more than one drug with interferon-gamma may kill more tumor cells. This phase I/II trial is studying the side effects and best dose of giving fluorouracil together with phenylbutyrate, indomethacin, and interferon-gamma and to see how well it works in treating patients with stage IV colorectal cancer
NCT00004767 ↗ Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders Completed Johns Hopkins University Phase 2 1985-01-01 OBJECTIVES: I. Assess the safety and efficacy of sodium phenylbutyrate, sodium benzoate, sodium phenylacetate, and dietary intervention in patients with urea cycle disorders.
NCT00004767 ↗ Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders Completed National Center for Research Resources (NCRR) Phase 2 1985-01-01 OBJECTIVES: I. Assess the safety and efficacy of sodium phenylbutyrate, sodium benzoate, sodium phenylacetate, and dietary intervention in patients with urea cycle disorders.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Sodium Phenylbutyrate

Condition Name

Condition Name for Sodium Phenylbutyrate
Intervention Trials
Urea Cycle Disorders 6
Myelodysplastic Syndromes 3
Leukemia 3
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Condition MeSH

Condition MeSH for Sodium Phenylbutyrate
Intervention Trials
Urea Cycle Disorders, Inborn 9
Disease 7
Myelodysplastic Syndromes 5
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Clinical Trial Locations for Sodium Phenylbutyrate

Trials by Country

Trials by Country for Sodium Phenylbutyrate
Location Trials
United States 106
Canada 4
Spain 3
Italy 3
United Kingdom 2
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Trials by US State

Trials by US State for Sodium Phenylbutyrate
Location Trials
New York 13
Texas 12
Maryland 9
California 8
Pennsylvania 8
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Clinical Trial Progress for Sodium Phenylbutyrate

Clinical Trial Phase

Clinical Trial Phase for Sodium Phenylbutyrate
Clinical Trial Phase Trials
Phase 4 2
Phase 3 4
Phase 2/Phase 3 3
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Clinical Trial Status

Clinical Trial Status for Sodium Phenylbutyrate
Clinical Trial Phase Trials
Completed 27
Recruiting 4
Terminated 3
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Clinical Trial Sponsors for Sodium Phenylbutyrate

Sponsor Name

Sponsor Name for Sodium Phenylbutyrate
Sponsor Trials
Horizon Pharma Ireland, Ltd., Dublin Ireland 6
National Cancer Institute (NCI) 5
Sidney Kimmel Comprehensive Cancer Center 3
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Sponsor Type

Sponsor Type for Sodium Phenylbutyrate
Sponsor Trials
Other 47
NIH 13
Industry 10
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