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Last Updated: March 29, 2024

CLINICAL TRIALS PROFILE FOR SODIUM MONOFLUOROPHOSPHATE


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All Clinical Trials for Sodium Monofluorophosphate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00708097 ↗ In Situ Caries Efficacy of Fluoride Toothpastes Completed GlaxoSmithKline Phase 3 2008-04-01 This study is to evaluate the effect of fluoride dentifrices on enamel with artificial caries lesions in an in situ model
NCT00708123 ↗ In Situ Caries of Fluoride Toothpastes Completed GlaxoSmithKline Phase 3 2007-11-01 This study is to evaluate the effect of fluoride dentifrices on enamel with artificial caries lesions in an in situ model.
NCT00759031 ↗ Investigation of Dental Plaque and Gingival Index Completed Colgate Palmolive Phase 3 2008-02-01 Investigation of inhibitory effect of prototype toothpaste on dental plaque formation via modified gingival margin plaque index method.
NCT01589458 ↗ Fluoride Availability in Saliva After Use of Sodium Fluoride or Monofluorophosphate Toothpastes Completed University of Campinas, Brazil Phase 1 2011-08-01 Considering the widespread use of sodium fluoride (NaF) and monofluorophosphate (MFP) based toothpastes, the present study aim to evaluate F availability in saliva after use of the top-selling Brazilian toothpastes. In a blind, crossover clinical trial study, volunteers will brush their teeth with one of the following toothpastes: 1) non-fluoride toothpaste (negative control group); 2) NaF/silica based toothpaste 3)MFP/calcium carbonate based toothpaste. After brushing, a rinse with purified water will be performed. Unstimulated saliva will be collected before and up to 60 min after brushing. Ionic fluoride and total soluble fluoride (corresponding to the sum of fluoride as ion and as MFP) will be determined after acid treatment of salivary samples to hydrolyze MFP. Fluoride will be determined using an ion selective electrode.
NCT01592851 ↗ Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity Completed GlaxoSmithKline Phase 3 2012-04-01 A study to compare the efficacy of a test dentifrice against a control dentifrice in reducing dentinal hypersensitivity over a two week treatment period.
NCT01592864 ↗ The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity Completed GlaxoSmithKline Phase 3 2012-03-01 A study to compare the efficacy of a test dentifrice against a control dentifrice in reducing dentinal hypersensitivity over an eight week treatment period.
NCT01657877 ↗ Anti-caries Potential of a Sodium Monofluorophosphate and Calcium Sodium Phosphosilicate Dentifrice Completed GlaxoSmithKline Phase 2 2012-05-01 In situ study to compare treatment effect on enamel remineralization potential, measured by surface microhardness recovery (SMHR) and Enamel Fluoride Uptake (EFU). The study will explore the efficacy of an experimental sodium monofluorophosphate (SMFP) dentifrice containing calcium sodium phosphosilicate (CSP) in comparison to an experimental SMFP only dentifrice.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Sodium Monofluorophosphate

Condition Name

Condition Name for Sodium Monofluorophosphate
Intervention Trials
Dentine Hypersensitivity 5
Caries 4
Dentin Sensitivity 3
Gingivitis 2
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Condition MeSH

Condition MeSH for Sodium Monofluorophosphate
Intervention Trials
Hypersensitivity 9
Dentin Sensitivity 8
Gingivitis 2
Dental Caries 1
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Clinical Trial Locations for Sodium Monofluorophosphate

Trials by Country

Trials by Country for Sodium Monofluorophosphate
Location Trials
United States 11
Ireland 2
Brazil 1
Egypt 1
Chile 1
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Trials by US State

Trials by US State for Sodium Monofluorophosphate
Location Trials
Indiana 5
Nevada 4
Texas 1
New York 1
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Clinical Trial Progress for Sodium Monofluorophosphate

Clinical Trial Phase

Clinical Trial Phase for Sodium Monofluorophosphate
Clinical Trial Phase Trials
Phase 4 2
Phase 3 11
Phase 2 2
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Clinical Trial Status

Clinical Trial Status for Sodium Monofluorophosphate
Clinical Trial Phase Trials
Completed 17
Unknown status 1
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Clinical Trial Sponsors for Sodium Monofluorophosphate

Sponsor Name

Sponsor Name for Sodium Monofluorophosphate
Sponsor Trials
GlaxoSmithKline 11
University of Campinas, Brazil 2
University of Chile 1
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Sponsor Type

Sponsor Type for Sodium Monofluorophosphate
Sponsor Trials
Industry 14
Other 5
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