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Generated: December 10, 2018

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CLINICAL TRIALS PROFILE FOR SEVELAMER HYDROCHLORIDE

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Clinical Trials for Sevelamer Hydrochloride

Trial ID Title Status Sponsor Phase Summary
NCT00018135 Parathyroid Hormone Levels in Relation to the Phosphorus Content of Meals Completed National Center for Research Resources (NCRR) N/A Patients on hemodialysis tend to have chronic elevations in the level of phosphorus in the blood and a secondary increase in the iPTH level. This chronic elevation in iPTH can have adverse consequences, thus a variety of phosphate binders are given in an attempt to decrease the absorption of phosphorus present in the normal diet. Some preliminary studies have indicated that the iPTH level may change based on the amount of phosphorus present in a meal prior to any significant absorption of phosphorus. If this is true in hemodialysis patients, then the timing of the administration of phosphate binders in relation to the ingestion of meals needs to be considered
NCT00151918 Efficacy and Safety of Lanthanum Carbonate and Sevelamer Hydrochloride in Patients Receiving Haemodialysis for End Stage Renal Disease Completed Shire Phase 3 The purpose of this study is to assess phosphate reduction and control in patients with End Stage Renal Disease treated with either lanthanum carbonate or sevelamer hydrochloride
NCT00196755 Study of Safety and Efficacy of Renagel® Compared With Calcium Acetate in Patients With Peritoneal Dialysis Completed Genzyme, a Sanofi Company Phase 3 The purpose of this study is to demonstrate that sevelamer hydrochloride is non-inferior to calcium acetate for the treatment of hyperphosphataemia in patients receiving peritoneal dialysis.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Sevelamer Hydrochloride

Condition Name

Condition Name for Sevelamer Hydrochloride
Intervention Trials
Chronic Kidney Disease 19
Hyperphosphatemia 15
Kidney Failure, Chronic 5
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Condition MeSH

Condition MeSH for Sevelamer Hydrochloride
Intervention Trials
Kidney Diseases 39
Renal Insufficiency, Chronic 36
Hyperphosphatemia 21
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Clinical Trial Locations for Sevelamer Hydrochloride

Trials by Country

Trials by Country for Sevelamer Hydrochloride
Location Trials
United States 167
France 18
United Kingdom 16
Italy 12
Japan 12
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Trials by US State

Trials by US State for Sevelamer Hydrochloride
Location Trials
New York 13
California 12
Texas 12
Illinois 10
Colorado 9
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Clinical Trial Progress for Sevelamer Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Sevelamer Hydrochloride
Clinical Trial Phase Trials
Phase 4 12
Phase 3 21
Phase 2 16
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Clinical Trial Status

Clinical Trial Status for Sevelamer Hydrochloride
Clinical Trial Phase Trials
Completed 46
Recruiting 11
Not yet recruiting 4
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Clinical Trial Sponsors for Sevelamer Hydrochloride

Sponsor Name

Sponsor Name for Sevelamer Hydrochloride
Sponsor Trials
Genzyme, a Sanofi Company 19
Shire 7
Fresenius Medical Care North America 4
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Sponsor Type

Sponsor Type for Sevelamer Hydrochloride
Sponsor Trials
Industry 50
Other 46
NIH 4
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Serving hundreds of leading biopharmaceutical companies globally:

Accenture
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McKinsey
Boehringer Ingelheim
Daiichi Sankyo
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Chinese Patent Office

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