CLINICAL TRIALS PROFILE FOR SEPTOCAINE

All Clinical Trials for Septocaine

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT01350050 ↗	Topical Pharyngeal Anesthesia With Articaine for Gastroscopy	Completed	Helsinki University Central Hospital	Phase 4	2009-09-01	Topical Pharyngeal anesthesia (TPA) is widely used during upper endoscopy. Articaine is local anaesthetic that have not been previously evaluated in pharyngeal anesthesia for upper endoscopy. The aim of this study was to compare pharyngeal anesthesia with 4% articaine to placebo (Na0,9%) during gastroscopy in terms of benefit on patients' and endoscopists' satisfaction.
NCT01951820 ↗	Comparison of Two Topical Anesthetics: Benzocaine Versus Pliaglis	Completed	American Association of Endodontists	Phase 4	2013-08-01	The efficacy of the topical anesthetics will be determined by how much pain the patient felt (using a Heft-Parker pain analog scale) upon needle penetration.
NCT01951820 ↗	Comparison of Two Topical Anesthetics: Benzocaine Versus Pliaglis	Completed	University of Michigan	Phase 4	2013-08-01	The efficacy of the topical anesthetics will be determined by how much pain the patient felt (using a Heft-Parker pain analog scale) upon needle penetration.
NCT03962634 ↗	Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Pediatric	Terminated	Virginia Commonwealth University	Phase 2	2019-08-28	The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine needle anesthesia.
NCT04104789 ↗	Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - General	Withdrawn	Virginia Commonwealth University	Phase 2	2020-09-01	The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine needle anesthesia.
NCT04105985 ↗	Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Endodontics	Withdrawn	Virginia Commonwealth University	Phase 2	2020-08-01	The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine needle anesthesia.
NCT04961268 ↗	Effect of Preoperative Oral Tramadol on Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis	Completed	Alfarabi Colleges	N/A	2020-06-01	Aim: The purpose of this prospective, randomized, double-blind, controlled study was to compare the preoperative oral tramadol medication with ibuprofen and acetaminophen on the success of inferior alveolar nerve blocks (IANB) of mandibular posterior teeth in patients experiencing symptomatic irreversible pulpitis. Methodology: The study included five study groups, each consists of 50 patients who exhibited symptomatic irreversible pulpitis of a mandibular first or second molar. The patients received identically appearing capsules containing either tramadol 50 mg, tramadol 100 mg, ibuprofen 600 mg, ibuprofen 600 mg/acetaminophen 1000 mg or placebo by mouth 60 min before the administration of an IANB. Endodontic access was begun 15 min after completion of the IANB, and all patients used for data analysis had profound lip numbness. The IANB success was defined as no or mild pain (visual analog scale recordings) on pulpal access or instrumentation. The data were analysed using chi-square χ2 and Kruskal-Wallis tests.

Clinical Trial Conditions for Septocaine

Condition Name

Condition Name for Septocaine
Intervention	Trials
Apical Periodontitis	3
Caries,Dental	3
Anesthesia of Mucous Membrane	1
Gastroscopy	1

Condition MeSH

Condition MeSH for Septocaine
Intervention	Trials
Periodontitis	3
Periapical Periodontitis	3
Dental Caries	3
Pulpitis	1

Clinical Trial Locations for Septocaine

Trials by Country

Trials by Country for Septocaine
Location	Trials
United States	4
Finland	1
Saudi Arabia	1

Trials by US State

Trials by US State for Septocaine
Location	Trials
Virginia	3
Michigan	1

Clinical Trial Progress for Septocaine

Clinical Trial Phase

Clinical Trial Phase for Septocaine
Clinical Trial Phase	Trials
Phase 4	2
Phase 2	3
N/A	1

Clinical Trial Status

Clinical Trial Status for Septocaine
Clinical Trial Phase	Trials
Completed	3
Withdrawn	2
Terminated	1

Clinical Trial Sponsors for Septocaine

Sponsor Name

Sponsor Name for Septocaine
Sponsor	Trials
Virginia Commonwealth University	3
Helsinki University Central Hospital	1
American Association of Endodontists	1

Sponsor Type

Sponsor Type for Septocaine
Sponsor	Trials
Other	7