Irinotecan and Selenium in Treating Patients With Advanced Solid Tumors
Roswell Park Cancer Institute
RATIONALE: Drugs used in chemotherapy, such as irinotecan, work in different ways to stop the
growth of tumor cells, either by killing the cells or by stopping them from dividing.
Selenium may allow higher doses of irinotecan to be given. Giving irinotecan together with
selenium may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of selenium when given
together with irinotecan in treating patients with advanced solid tumors.
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