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Last Updated: October 21, 2019

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CLINICAL TRIALS PROFILE FOR RUXOLITINIB PHOSPHATE

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Clinical Trials for Ruxolitinib Phosphate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01164163 INCB18424 in Treating Young Patients With Relapsed or Refractory Solid Tumor, Leukemia, or Myeloproliferative Disease Completed National Cancer Institute (NCI) Phase 1 2010-09-01 RATIONALE: INCB18424 (Ruxolitinib) may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase 1 clinical trial is studying the side effects and best dose of INCB18424 in treating young patients with relapsed or refractory solid tumor, leukemia, or myeloproliferative disease.
NCT01164163 INCB18424 in Treating Young Patients With Relapsed or Refractory Solid Tumor, Leukemia, or Myeloproliferative Disease Completed Children's Oncology Group Phase 1 2010-09-01 RATIONALE: INCB18424 (Ruxolitinib) may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase 1 clinical trial is studying the side effects and best dose of INCB18424 in treating young patients with relapsed or refractory solid tumor, leukemia, or myeloproliferative disease.
NCT01431209 Ruxolitinib Phosphate (Oral JAK Inhibitor INCB18424) in Treating Patients With Relapsed or Refractory Diffuse Large B-Cell or Peripheral T-Cell Non-Hodgkin Lymphoma Recruiting Incyte Corporation Phase 2 2011-08-01 This phase II trial studies how well giving ruxolitinib phosphate (oral JAK inhibitor INCB18424) works in treating patients with relapsed or refractory diffuse large B-cell or peripheral T-cell non-hodgkin lymphoma and are ineligible to stem cell transplant or have recurrent disease after stem cell transplant. Ruxolitinib phosphate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
NCT01431209 Ruxolitinib Phosphate (Oral JAK Inhibitor INCB18424) in Treating Patients With Relapsed or Refractory Diffuse Large B-Cell or Peripheral T-Cell Non-Hodgkin Lymphoma Recruiting University of Nebraska Phase 2 2011-08-01 This phase II trial studies how well giving ruxolitinib phosphate (oral JAK inhibitor INCB18424) works in treating patients with relapsed or refractory diffuse large B-cell or peripheral T-cell non-hodgkin lymphoma and are ineligible to stem cell transplant or have recurrent disease after stem cell transplant. Ruxolitinib phosphate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Ruxolitinib Phosphate

Condition Name

Condition Name for Ruxolitinib Phosphate
Intervention Trials
Secondary Myelofibrosis 4
Primary Myelofibrosis 4
HER2/Neu Negative 1
Unspecified Childhood Solid Tumor, Protocol Specific 1
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Condition MeSH

Condition MeSH for Ruxolitinib Phosphate
Intervention Trials
Leukemia 4
Primary Myelofibrosis 4
Leukemia, Myeloid 3
Neoplasm Metastasis 2
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Clinical Trial Locations for Ruxolitinib Phosphate

Trials by Country

Trials by Country for Ruxolitinib Phosphate
Location Trials
United States 74
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Trials by US State

Trials by US State for Ruxolitinib Phosphate
Location Trials
California 5
New York 4
Texas 4
Washington 3
Pennsylvania 3
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Clinical Trial Progress for Ruxolitinib Phosphate

Clinical Trial Phase

Clinical Trial Phase for Ruxolitinib Phosphate
Clinical Trial Phase Trials
Phase 2 6
Phase 1/Phase 2 1
Phase 1 3
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Clinical Trial Status

Clinical Trial Status for Ruxolitinib Phosphate
Clinical Trial Phase Trials
Recruiting 7
Not yet recruiting 1
Active, not recruiting 1
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Clinical Trial Sponsors for Ruxolitinib Phosphate

Sponsor Name

Sponsor Name for Ruxolitinib Phosphate
Sponsor Trials
National Cancer Institute (NCI) 9
Mayo Clinic 2
City of Hope Medical Center 2
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Sponsor Type

Sponsor Type for Ruxolitinib Phosphate
Sponsor Trials
Other 12
NIH 10
Industry 1
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