Exercise And Rosuvastatin Treatment: Is There an Anti-Inflammatory Synergy?
The purpose of this study is to determine whether the effects of rosuvastatin treatment and
exercise training can be synergistic, with respect to the innate immune receptor TLR4,
markers of systemic inflammation, and stimulated production of inflammatory cytokines, in
hypercholesterolemic subjects. It is hypothesized that a rosuvastatin and exercise
intervention will synergistically lower measured variables, so as to be anti-inflammatory.
Study to Evaluate the Long-Term Safety and Efficacy of ABT-335, in Combination With Three Different Statins in Subjects With Mixed Dyslipidemia.
The primary purpose of this study is to test the safety and the effects of using an
investigational drug regimen; once daily ABT-335 (Investigational drug) administered in
combination with once daily atorvastatin calcium, rosuvastatin calcium or simvastatin in
patients with abnormal lipid levels in the blood.
Evaluate Safety and Efficacy of ABT-335 in Combination With Rosuvastatin Calcium in Subjects With Multiple Abnormal Lipid Levels in the Blood
The purpose of this study is to compare the safety and efficacy of fenofibric acid (ABT-335)
+ rosuvastatin calcium combination therapy with ABT-335 and rosuvastatin calcium monotherapy
in subjects with multiple abnormal lipid levels in the blood.
Rosuvastatin in the Long-term Treatment of Hypercholesterolaemic Subjects With Coronary Heart Disease
The primary objective of this study is to evaluate that 76 weeks of treatment with
rosuvastatin calcium 2.5-20 mg results in no progression of coronary artery atherosclerotic
volume as measured by intravascular ultrasonography (IVUS) imaging in hypercholesterolaemic
subjects with coronary heart disease (CHD).
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