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Generated: February 23, 2019

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CLINICAL TRIALS PROFILE FOR RETISERT

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Clinical Trials for Retisert

Trial ID Title Status Sponsor Phase Summary
NCT00032396 A Study to Evaluate Retisert in the Treatment of Patients With the "Wet" Form of Age-Related Macular Degeneration Unknown status Bausch & Lomb Incorporated Phase 2 A study evaluating Retisert in patients with age-related macular degeneration
NCT00032396 A Study to Evaluate Retisert in the Treatment of Patients With the "Wet" Form of Age-Related Macular Degeneration Unknown status Control Delivery Systems Phase 2 A study evaluating Retisert in patients with age-related macular degeneration
NCT00502541 Efficacy of Fluocinolone Acetonide Intravitreal Implant in Diabetic Macular Edema Completed Bausch & Lomb Incorporated Phase 2/Phase 3 This was a multi-center, randomized, masked, parallel-group, controlled study in patients with diabetic macular edema, comparing RetisertTM (0.59 mg) with control therapy (standard of care (SOC) - repeat macular grid laser or observation). The objective was to evaluate the safety and efficacy of the intravitreal fluocinolone acetonide implant in the treatment of patients with diabetic macular edema.
NCT00543296 Re-implantation of a Fluocinolone Acetonide Implant for Non-infectious Uveitis Affecting the Posterior Segment Completed Bausch & Lomb Incorporated Phase 4 The purpose of this study is to collect data on patients with severe uveitis that have required re-implantation of the sustained-release fluocinolone drug delivery device due to depletion of study drug in their previous implanted device.
NCT00543296 Re-implantation of a Fluocinolone Acetonide Implant for Non-infectious Uveitis Affecting the Posterior Segment Completed Duke University Phase 4 The purpose of this study is to collect data on patients with severe uveitis that have required re-implantation of the sustained-release fluocinolone drug delivery device due to depletion of study drug in their previous implanted device.
NCT00570479 Prophylactic Anecortave Acetate in Patients With a Retisert Implant Completed Alcon Research Phase 1 Retisert implant is an effective therapy for controlling inflammation in patients with non-infectious posterior uveitis. One of the major complications of this device is the development of elevated intraocular pressure (IOP) following implantation in 60% of patients. Glaucoma filtering is required in over 30% of patients at 2 years. Anecortave acetate (AA) has been shown to reduce steroid induced elevated IOP. The purpose of this study was to evaluate the ability of prophylactic anterior juxtascleral depot administration of AA to prevent this Retisert induced elevated IOP.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Retisert

Condition Name

Condition Name for Retisert
Intervention Trials
Diabetic Macular Edema 3
Uveitis, Posterior 2
Uveitis, Intermediate 1
Glaucoma 1
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Condition MeSH

Condition MeSH for Retisert
Intervention Trials
Uveitis 5
Macular Edema 3
Edema 3
Uveitis, Posterior 2
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Clinical Trial Locations for Retisert

Trials by Country

Trials by Country for Retisert
Location Trials
United States 5
India 1
China 1
Korea, Republic of 1
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Trials by US State

Trials by US State for Retisert
Location Trials
North Carolina 2
Maryland 1
Texas 1
Massachusetts 1
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Clinical Trial Progress for Retisert

Clinical Trial Phase

Clinical Trial Phase for Retisert
Clinical Trial Phase Trials
Phase 4 3
Phase 2/Phase 3 1
Phase 2 3
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Clinical Trial Status

Clinical Trial Status for Retisert
Clinical Trial Phase Trials
Completed 4
Unknown status 2
Recruiting 1
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Clinical Trial Sponsors for Retisert

Sponsor Name

Sponsor Name for Retisert
Sponsor Trials
Bausch & Lomb Incorporated 4
Asan Medical Center 1
Control Delivery Systems 1
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Sponsor Type

Sponsor Type for Retisert
Sponsor Trials
Other 10
Industry 7
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Serving hundreds of leading biopharmaceutical companies globally:

Baxter
Johnson and Johnson
Queensland Health
Farmers Insurance
Express Scripts
Boehringer Ingelheim
Accenture
Healthtrust
Merck

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