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CLINICAL TRIALS PROFILE FOR PROGESTERONE

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Clinical Trials for Progesterone

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00000175	The Effects of Sex Hormones on Cognition and Mood in Older Adults	Terminated	National Institute on Aging (NIA)	N/A	This study is investigating the effects of hormone replacement therapy on memory, mental abilities and mood in older adults aged 65-90. During the nine month long study, men will take testosterone for three months and women will take estrogen for three months. At four points during the study (once every three months), participants will complete a test battery and have blood drawn.
NCT00000176	Alzheimer's Disease Prevention Trial	Completed	National Institute on Aging (NIA)	Phase 3	This is a three-year study to determine if estrogens can prevent memory loss and Alzheimer's disease in women with a family history of Alzheimer's disease.
NCT00000295	Progesterone Treatment in Female Smokers - 12	Completed	University of Minnesota - Clinical and Translational Science Institute	Phase 2	The purpose of this study is to investigate progesterone effects in female smokers
NCT00000295	Progesterone Treatment in Female Smokers - 12	Completed	National Institute on Drug Abuse (NIDA)	Phase 2	The purpose of this study is to investigate progesterone effects in female smokers
NCT00000466	Postmenopausal Estrogen/Progestin Interventions (PEPI)	Completed	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Phase 3	To assess the effects of various postmenopausal estrogen replacement therapies on selected cardiovascular risk factors, including high density lipoprotein cholesterol, systolic blood pressure, fibrinogen, and insulin and on osteoporosis risk factors. Conducted in collaboration with the National Institute of Child Health and Human Development, the National Institute of Arthritis and Musculoskeletal and Skin Diseases, The National Institute of Diabetes and Digestive and Kidney Diseases, and the National Institute on Aging. The extended follow-up is for 3 years focusing on endometrium and breast evaluation.

Clinical Trial Conditions for Progesterone

Condition Name

Condition Name for Progesterone
Intervention	Trials
Breast Cancer	136
Infertility	105
Polycystic Ovary Syndrome	30
Stage IV Breast Cancer	23

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Condition MeSH

Condition MeSH for Progesterone
Intervention	Trials
Breast Neoplasms	224
Infertility	126
Premature Birth	57
Polycystic Ovary Syndrome	42

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Clinical Trial Locations for Progesterone

Trials by Country

Trials by Country for Progesterone
Location	Trials
United Kingdom	70
Egypt	53
Italy	50
Spain	47
China	42

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Trials by US State

Trials by US State for Progesterone
Location	Trials
California	104
New York	95
Texas	83
Illinois	74
Florida	70

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Clinical Trial Progress for Progesterone

Clinical Trial Phase

Clinical Trial Phase for Progesterone
Clinical Trial Phase	Trials
Phase 4	148
Phase 3	171
Phase 2/Phase 3	32

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Clinical Trial Status

Clinical Trial Status for Progesterone
Clinical Trial Phase	Trials
Completed	310
Recruiting	196
Not yet recruiting	72

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Clinical Trial Sponsors for Progesterone

Sponsor Name

Sponsor Name for Progesterone
Sponsor	Trials
National Cancer Institute (NCI)	104
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	38
Cairo University	17

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Sponsor Type

Sponsor Type for Progesterone
Sponsor	Trials
Other	911
Industry	221
NIH	203

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