Effects of Atorvastatin Versus Probucol on Small Dense LDL
Yokohama City University Medical Center
Small dense low-density lipoprotein (LDL) plays an important role in causing glomerular
injury through conversion to an oxidatively modified form of LDL. However, few studies
evaluated the effects of antilipidemic agents on the LDL particle size and renoprotective
actions in hyperlipidemic patients with non-diabetic nephropathy.
A Study of the Antioxidant Probucol Combined With Valsartan in Patients With IgA Nephropathy
Guangdong General Hospital
a statement of the study hypothesis:the effect of valsartan in patients with IgA nephropathy
have been proved,and the efficacy of probucol in combination with valsartan is to be proved
in patients with IgA nephropathy.
This is a prospective randomized controlled, double blinded pilot study to identify the
efficacy of probucol in combination with valsartan in patients with IgA nephropathy. The
renal function deterioration will be the primary outcome studied. The expected study
duration will be 36 months.
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