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Last Updated: October 15, 2019

DrugPatentWatch Database Preview

CLINICAL TRIALS PROFILE FOR PROBUCOL

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Clinical Trials for Probucol

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00276133 Effects of Atorvastatin Versus Probucol on Small Dense LDL Completed Yokohama City University Medical Center Phase 4 2004-01-01 Small dense low-density lipoprotein (LDL) plays an important role in causing glomerular injury through conversion to an oxidatively modified form of LDL. However, few studies evaluated the effects of antilipidemic agents on the LDL particle size and renoprotective actions in hyperlipidemic patients with non-diabetic nephropathy.
NCT00426348 A Study of the Antioxidant Probucol Combined With Valsartan in Patients With IgA Nephropathy Completed Guangdong General Hospital Phase 4 2007-05-01 a statement of the study hypothesis:the effect of valsartan in patients with IgA nephropathy have been proved,and the efficacy of probucol in combination with valsartan is to be proved in patients with IgA nephropathy. This is a prospective randomized controlled, double blinded pilot study to identify the efficacy of probucol in combination with valsartan in patients with IgA nephropathy. The renal function deterioration will be the primary outcome studied. The expected study duration will be 36 months.
NCT00549978 Safety and Pharmacokinetics of Probucol and Cilostazol Completed Otsuka Pharmaceutical Co., Ltd. Phase 4 2007-10-01 to investigate the safety and pharmacokinetics, in healthy adult male subjects
NCT00549978 Safety and Pharmacokinetics of Probucol and Cilostazol Completed Korea Otsuka Pharmaceutical Co., Ltd. Phase 4 2007-10-01 to investigate the safety and pharmacokinetics, in healthy adult male subjects
NCT00655330 Probucol Combined With Valsartan in Reducing Proteinuria in Diabetes Nephropathy Active, not recruiting Guangdong General Hospital N/A 2008-05-01 This is a prospective randomized controlled, open-labeled study to identify the efficacy of probucol in combination with valsartan in patients with Diabetes nephropathy. The reduction of urinary albumin or proteinuria will be the primary outcome studied. The expected study duration will be 48 weeks.
NCT00823849 Study of Cilostazol and Probucol to Assess Their Effects on Atherosclerosis Related Biomarker Completed Otsuka Beijing Research Institute Phase 4 2008-10-01 1. To evaluate the efficacy of Cilostazol and Probucol alone and in combination on atherosclerosis related biomarker 2. To evaluate the safety of Cilostazol and Probucol alone and in combination on atherosclerosis related biomarker
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Probucol

Condition Name

Condition Name for Probucol
Intervention Trials
Healthy 3
Brain Ischemia 2
Type 2 Diabetes Mellitus 2
Diabetic Nephropathy 2
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Condition MeSH

Condition MeSH for Probucol
Intervention Trials
Kidney Diseases 5
Ischemia 3
Atherosclerosis 3
Cerebral Hemorrhage 2
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Clinical Trial Locations for Probucol

Trials by Country

Trials by Country for Probucol
Location Trials
Korea, Republic of 22
China 10
Japan 1
Philippines 1
Canada 1
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Clinical Trial Progress for Probucol

Clinical Trial Phase

Clinical Trial Phase for Probucol
Clinical Trial Phase Trials
Phase 4 13
Phase 3 1
Phase 2 2
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Clinical Trial Status

Clinical Trial Status for Probucol
Clinical Trial Phase Trials
Completed 12
Active, not recruiting 4
Not yet recruiting 2
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Clinical Trial Sponsors for Probucol

Sponsor Name

Sponsor Name for Probucol
Sponsor Trials
Korea Otsuka Pharmaceutical Co., Ltd. 8
Otsuka Beijing Research Institute 7
Asan Medical Center 2
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Sponsor Type

Sponsor Type for Probucol
Sponsor Trials
Industry 16
Other 11
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