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Last Updated: June 26, 2022

CLINICAL TRIALS PROFILE FOR PRALATREXATE


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All Clinical Trials for Pralatrexate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00004238 ↗ 10-Propargyl-10-Deazaaminopterin in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer Completed National Cancer Institute (NCI) Phase 2 1999-07-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of 10-propargyl-10-deazaaminopterin in treating patients who have stage IIIB or stage IV non-small cell lung cancer.
NCT00004238 ↗ 10-Propargyl-10-Deazaaminopterin in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer Completed Memorial Sloan Kettering Cancer Center Phase 2 1999-07-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of 10-propargyl-10-deazaaminopterin in treating patients who have stage IIIB or stage IV non-small cell lung cancer.
NCT00024245 ↗ 10-Propargyl-10-Deazaaminopterin Plus Probenecid in Treating Patients With Advanced Solid Tumors Completed National Cancer Institute (NCI) Phase 1 2001-05-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Probenecid may increase the effectiveness of 10-propargyl-10-deazaaminopterin by making tumor cells more sensitive to the drug. PURPOSE: Phase I trial to study the effectiveness of combining 10-propargyl-10-deazaaminopterin and probenecid in treating patients who have advanced solid tumors.
NCT00024245 ↗ 10-Propargyl-10-Deazaaminopterin Plus Probenecid in Treating Patients With Advanced Solid Tumors Completed Memorial Sloan Kettering Cancer Center Phase 1 2001-05-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Probenecid may increase the effectiveness of 10-propargyl-10-deazaaminopterin by making tumor cells more sensitive to the drug. PURPOSE: Phase I trial to study the effectiveness of combining 10-propargyl-10-deazaaminopterin and probenecid in treating patients who have advanced solid tumors.
NCT00052442 ↗ 10-Propargyl-10-Deazaaminopterin in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Hodgkin's Lymphoma Completed Memorial Sloan Kettering Cancer Center Phase 1/Phase 2 2002-08-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of 10-propargyl-10-deazaaminopterin in treating patients who have recurrent or refractory non-Hodgkin's lymphoma or Hodgkin's lymphoma.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Pralatrexate

Condition Name

Condition Name for Pralatrexate
Intervention Trials
Peripheral T-cell Lymphoma 5
Refractory Peripheral T-Cell Lymphoma 3
Cutaneous T-cell Lymphoma 2
PTCL 2
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Condition MeSH

Condition MeSH for Pralatrexate
Intervention Trials
Lymphoma 23
Lymphoma, T-Cell 20
Lymphoma, T-Cell, Peripheral 15
Lymphoma, Non-Hodgkin 6
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Clinical Trial Locations for Pralatrexate

Trials by Country

Trials by Country for Pralatrexate
Location Trials
United States 133
France 9
United Kingdom 9
Hungary 8
India 7
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Trials by US State

Trials by US State for Pralatrexate
Location Trials
New York 21
California 13
Texas 8
Washington 7
New Jersey 7
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Clinical Trial Progress for Pralatrexate

Clinical Trial Phase

Clinical Trial Phase for Pralatrexate
Clinical Trial Phase Trials
Phase 4 1
Phase 3 4
Phase 2 14
[disabled in preview] 18
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Clinical Trial Status

Clinical Trial Status for Pralatrexate
Clinical Trial Phase Trials
Completed 25
Recruiting 5
Withdrawn 4
[disabled in preview] 3
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Clinical Trial Sponsors for Pralatrexate

Sponsor Name

Sponsor Name for Pralatrexate
Sponsor Trials
Spectrum Pharmaceuticals, Inc 16
Acrotech Biopharma LLC 10
National Cancer Institute (NCI) 7
[disabled in preview] 10
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Sponsor Type

Sponsor Type for Pralatrexate
Sponsor Trials
Industry 40
Other 39
NIH 7
[disabled in preview] 1
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