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Last Updated: May 22, 2024

CLINICAL TRIALS PROFILE FOR POLYMYXIN B SULFATE


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All Clinical Trials for Polymyxin B Sulfate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000635 ↗ Treatment of Acyclovir-Resistant Mucocutaneous Herpes Simplex Disease in Patients With AIDS: Open Label Pilot Study of Topical Trifluridine Completed Glaxo Wellcome N/A 1969-12-31 To determine the safety, effectiveness, and toxicity of topical (local) trifluridine in treating mucocutaneous (at the nasal, oral, vaginal, and anal openings) Herpes simplex virus ( HSV ) disease that has shown resistance to acyclovir in HIV-infected patients. HSV infection in patients with AIDS is often associated with skin sores and frequent recurrences. Treatment with the drug acyclovir results in healing for most patients, but repeated treatment sometimes results in resistance of the virus to acyclovir. Thus, when this happens, other treatments need to be used. Trifluridine is an antiviral drug that is used for the treatment of Herpes infections that occur in the eye. This study attempts to determine if trifluridine is useful for treating HSV sores that have not healed after treatment with acyclovir.
NCT00000635 ↗ Treatment of Acyclovir-Resistant Mucocutaneous Herpes Simplex Disease in Patients With AIDS: Open Label Pilot Study of Topical Trifluridine Completed National Institute of Allergy and Infectious Diseases (NIAID) N/A 1969-12-31 To determine the safety, effectiveness, and toxicity of topical (local) trifluridine in treating mucocutaneous (at the nasal, oral, vaginal, and anal openings) Herpes simplex virus ( HSV ) disease that has shown resistance to acyclovir in HIV-infected patients. HSV infection in patients with AIDS is often associated with skin sores and frequent recurrences. Treatment with the drug acyclovir results in healing for most patients, but repeated treatment sometimes results in resistance of the virus to acyclovir. Thus, when this happens, other treatments need to be used. Trifluridine is an antiviral drug that is used for the treatment of Herpes infections that occur in the eye. This study attempts to determine if trifluridine is useful for treating HSV sores that have not healed after treatment with acyclovir.
NCT00534391 ↗ Comparison of Combination Antibiotics Eyedrop to Artificial Tear in Hordeolum After Incision and Curettage Unknown status Chulalongkorn University Phase 3 2007-09-01 To compare the effectiveness of combined antibiotic ophthalmic solution (neomycin sulfate, polymyxin B sulfate and gramicidin) with placebo (artificial tear) in the treatment of hordeolum after incision and curettage
NCT01227863 ↗ Efficacy Maxinom® And Maxitrol® in Reducing The Signs And Symptoms Of Acute Bacterial Conjunctivitis Unknown status Azidus Brasil Phase 3 2011-02-01 The primary objective of this study is to evaluate, through clinical parameters, the effectiveness of your medicine topic Maxinom ® (dexamethasone, neomycin and polymyxin B - Union Chemicals), comparing it to the topical medication Maxitrol ® (dexamethasone, neomycin and polymyxin B - Alcon ) by the percentage of improvement (sustained response rate) at the end of treatment, among the products studied.
NCT02424357 ↗ Suture Contamination Rate in Adjustable Suture Strabismus Surgery Completed Bascom Palmer Eye Institute N/A 2015-07-01 1. To establish the culture positivity rate in adjustable suture strabismus surgery 2. To identify bacterial species and antibiotic susceptibility patterns of microorganisms cultured from suture material 3. To compare suture contamination rates with techniques to reduce the suture contamination rate
NCT02424357 ↗ Suture Contamination Rate in Adjustable Suture Strabismus Surgery Completed University of Miami N/A 2015-07-01 1. To establish the culture positivity rate in adjustable suture strabismus surgery 2. To identify bacterial species and antibiotic susceptibility patterns of microorganisms cultured from suture material 3. To compare suture contamination rates with techniques to reduce the suture contamination rate
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Polymyxin B Sulfate

Condition Name

Condition Name for Polymyxin B Sulfate
Intervention Trials
Acinetobacter Infections 1
Acute 1
Bacterial Conjunctivitis 1
Hepatic Encephalopathy 1
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Condition MeSH

Condition MeSH for Polymyxin B Sulfate
Intervention Trials
Infection 2
Infections 2
Strabismus 1
HIV Infections 1
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Clinical Trial Locations for Polymyxin B Sulfate

Trials by Country

Trials by Country for Polymyxin B Sulfate
Location Trials
United States 7
Thailand 1
Korea, Republic of 1
Brazil 1
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Trials by US State

Trials by US State for Polymyxin B Sulfate
Location Trials
Florida 1
New York 1
Missouri 1
Maryland 1
Illinois 1
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Clinical Trial Progress for Polymyxin B Sulfate

Clinical Trial Phase

Clinical Trial Phase for Polymyxin B Sulfate
Clinical Trial Phase Trials
Phase 3 2
N/A 2
Early Phase 1 1
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Clinical Trial Status

Clinical Trial Status for Polymyxin B Sulfate
Clinical Trial Phase Trials
Completed 3
Unknown status 2
Not yet recruiting 1
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Clinical Trial Sponsors for Polymyxin B Sulfate

Sponsor Name

Sponsor Name for Polymyxin B Sulfate
Sponsor Trials
Madonna Magdy Fahmy 1
Glaxo Wellcome 1
National Institute of Allergy and Infectious Diseases (NIAID) 1
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Sponsor Type

Sponsor Type for Polymyxin B Sulfate
Sponsor Trials
Other 5
Industry 2
NIH 1
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