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Generated: December 10, 2018

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CLINICAL TRIALS PROFILE FOR PIMECROLIMUS

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Clinical Trials for Pimecrolimus

Trial ID Title Status Sponsor Phase Summary
NCT00117377 Effects of Pimecrolimus Cream 1% on the Molecular and Cellular Profile of Adult Male Patients With Atopic Dermatitis Completed Novartis Phase 4 The purpose of this study is to identify how pimecrolimus cream 1% modifies the molecular and cellular changes associated with the post-lesional phase of atopic dermatitis (AD). Healthy volunteers and patients with atopic dermatitis will be studied.
NCT00119158 Combination Therapy for Atopic Dermatitis Completed Novartis Pharmaceuticals Phase 4 Atopic dermatitis is a chronic relapsing disease with acute flares. The standard therapy is to treat acute flares using topical medications. The two most common classes of topical medications for atopic dermatitis (AD) are topical corticosteroids and topical calcineurin inhibitors. Pimecrolimus and topical corticosteroids exert their activity by different mechanisms, there may be a synergistic effect of the combination therapy. Therefore, a combination therapy may provide a faster resolution of severe skin lesions and consequently reduce the duration of the topical corticosteroid treatment. Another benefit of the combination therapy maybe the use of a lower potency corticosteroid to achieve the same degree of clearance. The hypothesis of this trial is that the combination of the two agents will lead to faster clearance than the single agent of topical corticosteroids.
NCT00119158 Combination Therapy for Atopic Dermatitis Completed Children's Hospital of Philadelphia Phase 4 Atopic dermatitis is a chronic relapsing disease with acute flares. The standard therapy is to treat acute flares using topical medications. The two most common classes of topical medications for atopic dermatitis (AD) are topical corticosteroids and topical calcineurin inhibitors. Pimecrolimus and topical corticosteroids exert their activity by different mechanisms, there may be a synergistic effect of the combination therapy. Therefore, a combination therapy may provide a faster resolution of severe skin lesions and consequently reduce the duration of the topical corticosteroid treatment. Another benefit of the combination therapy maybe the use of a lower potency corticosteroid to achieve the same degree of clearance. The hypothesis of this trial is that the combination of the two agents will lead to faster clearance than the single agent of topical corticosteroids.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Pimecrolimus

Condition Name

Condition Name for Pimecrolimus
Intervention Trials
Atopic Dermatitis 25
Dermatitis, Atopic 5
Oral Lichen Planus 3
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Condition MeSH

Condition MeSH for Pimecrolimus
Intervention Trials
Dermatitis 36
Eczema 32
Dermatitis, Atopic 32
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Clinical Trial Locations for Pimecrolimus

Trials by Country

Trials by Country for Pimecrolimus
Location Trials
United States 140
Germany 12
Switzerland 3
Canada 2
Japan 2
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Trials by US State

Trials by US State for Pimecrolimus
Location Trials
California 8
North Carolina 7
Florida 7
Texas 7
Virginia 7
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Clinical Trial Progress for Pimecrolimus

Clinical Trial Phase

Clinical Trial Phase for Pimecrolimus
Clinical Trial Phase Trials
Phase 4 21
Phase 3 10
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Pimecrolimus
Clinical Trial Phase Trials
Completed 40
Recruiting 3
Terminated 3
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Clinical Trial Sponsors for Pimecrolimus

Sponsor Name

Sponsor Name for Pimecrolimus
Sponsor Trials
Novartis 22
Novartis Pharmaceuticals 7
Astellas Pharma Inc 3
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Sponsor Type

Sponsor Type for Pimecrolimus
Sponsor Trials
Industry 38
Other 33
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Serving hundreds of leading biopharmaceutical companies globally:

Baxter
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Merck
Citi
AstraZeneca
Federal Trade Commission
Fuji
Farmers Insurance

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