CLINICAL TRIALS PROFILE FOR PIMECROLIMUS
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All Clinical Trials for Pimecrolimus
Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
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NCT00117377 ↗ | Effects of Pimecrolimus Cream 1% on the Molecular and Cellular Profile of Adult Male Patients With Atopic Dermatitis | Completed | Novartis | Phase 4 | 2004-04-01 | The purpose of this study is to identify how pimecrolimus cream 1% modifies the molecular and cellular changes associated with the post-lesional phase of atopic dermatitis (AD). Healthy volunteers and patients with atopic dermatitis will be studied. |
NCT00119158 ↗ | Combination Therapy for Atopic Dermatitis | Completed | Novartis Pharmaceuticals | Phase 4 | 2004-10-01 | Atopic dermatitis is a chronic relapsing disease with acute flares. The standard therapy is to treat acute flares using topical medications. The two most common classes of topical medications for atopic dermatitis (AD) are topical corticosteroids and topical calcineurin inhibitors. Pimecrolimus and topical corticosteroids exert their activity by different mechanisms, there may be a synergistic effect of the combination therapy. Therefore, a combination therapy may provide a faster resolution of severe skin lesions and consequently reduce the duration of the topical corticosteroid treatment. Another benefit of the combination therapy maybe the use of a lower potency corticosteroid to achieve the same degree of clearance. The hypothesis of this trial is that the combination of the two agents will lead to faster clearance than the single agent of topical corticosteroids. |
NCT00119158 ↗ | Combination Therapy for Atopic Dermatitis | Completed | Children's Hospital of Philadelphia | Phase 4 | 2004-10-01 | Atopic dermatitis is a chronic relapsing disease with acute flares. The standard therapy is to treat acute flares using topical medications. The two most common classes of topical medications for atopic dermatitis (AD) are topical corticosteroids and topical calcineurin inhibitors. Pimecrolimus and topical corticosteroids exert their activity by different mechanisms, there may be a synergistic effect of the combination therapy. Therefore, a combination therapy may provide a faster resolution of severe skin lesions and consequently reduce the duration of the topical corticosteroid treatment. Another benefit of the combination therapy maybe the use of a lower potency corticosteroid to achieve the same degree of clearance. The hypothesis of this trial is that the combination of the two agents will lead to faster clearance than the single agent of topical corticosteroids. |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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