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CLINICAL TRIALS PROFILE FOR PERFLUTREN

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Clinical Trials for Perflutren

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00398281	Dutasteride Followed By Ultrasound-Guided Biopsy in Finding Prostate Cancer	Completed	National Cancer Institute (NCI)	Phase 3	RATIONALE: Diagnostic procedures, such as ultrasound-guided biopsy, may help find prostate cancer. Dutasteride may improve the ability of ultrasound-guided biopsy to find prostate cancer. It is not yet known whether dutasteride followed by ultrasound-guided biopsy is more effective than a placebo followed by ultrasound-guided biopsy in finding prostate cancer. PURPOSE: This randomized phase III trial is studying dutasteride and ultrasound-guided biopsy to see how well they find prostate cancer compared with a placebo and ultrasound-guided biopsy.
NCT00398281	Dutasteride Followed By Ultrasound-Guided Biopsy in Finding Prostate Cancer	Completed	Sidney Kimmel Cancer Center at Thomas Jefferson University	Phase 3	RATIONALE: Diagnostic procedures, such as ultrasound-guided biopsy, may help find prostate cancer. Dutasteride may improve the ability of ultrasound-guided biopsy to find prostate cancer. It is not yet known whether dutasteride followed by ultrasound-guided biopsy is more effective than a placebo followed by ultrasound-guided biopsy in finding prostate cancer. PURPOSE: This randomized phase III trial is studying dutasteride and ultrasound-guided biopsy to see how well they find prostate cancer compared with a placebo and ultrasound-guided biopsy.
NCT00507806	Microbubble-Enhanced Clotbust Treatment of Acute Ischemic Stroke	Terminated	ImaRx Therapeutics	Phase 1/Phase 2	The study is designed to examine the safety, tolerability, and activity of a combination of microbubbles (perflutren lipid microsphere [Definity®]) and continuous monitoring with 2 MHz transcranial Doppler ultrasound (TCD) as an adjunctive therapy to tissue plasminogen activator (tPA) treatment in subjects with acute ischemic stroke.

Clinical Trial Conditions for Perflutren

Condition Name

Condition Name for Perflutren
Intervention	Trials
Hepatocellular Carcinoma	2
Cystic Kidney Disease	2
Chest Pain	1

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Condition MeSH

Condition MeSH for Perflutren
Intervention	Trials
Carcinoma	3
Kidney Diseases, Cystic	2
Carcinoma, Renal Cell	2

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Clinical Trial Locations for Perflutren

Trials by Country

Trials by Country for Perflutren
Location	Trials
United States	13
United Kingdom	3

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Trials by US State

Trials by US State for Perflutren
Location	Trials
Pennsylvania	4
North Carolina	3
California	2
Massachusetts	1
Virginia	1

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Clinical Trial Progress for Perflutren

Clinical Trial Phase

Clinical Trial Phase for Perflutren
Clinical Trial Phase	Trials
Phase 3	1
Phase 2/Phase 3	1
Phase 2	3

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Clinical Trial Status

Clinical Trial Status for Perflutren
Clinical Trial Phase	Trials
Recruiting	5
Completed	3
Unknown status	3

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Clinical Trial Sponsors for Perflutren

Sponsor Name

Sponsor Name for Perflutren
Sponsor	Trials
Sidney Kimmel Cancer Center at Thomas Jefferson University	4
National Cancer Institute (NCI)	4
Lantheus Medical Imaging	2

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Sponsor Type

Sponsor Type for Perflutren
Sponsor	Trials
Other	17
NIH	6
Industry	4

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