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Last Updated: October 16, 2019

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CLINICAL TRIALS PROFILE FOR PENTOXIFYLLINE

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Clinical Trials for Pentoxifylline

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000579 Acute Respiratory Distress Syndrome Clinical Network (ARDSNet) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 1994-09-01 The purposes of this study are to assess rapidly innovative treatment methods in patients with adult respiratory distress syndrome (ARDS) as well as those at risk of developing ARDS and to create a network of interactive Critical Care Treatment Groups (CCTGs) to establish and maintain the required infrastructure to perform multiple therapeutic trials that may involve investigational drugs, approved agents not currently used for treatment of ARDS, or treatments currently used but whose efficacy has not been well documented.
NCT00000646 Pentoxifylline (Trental) as a Modulator of Tumor Necrosis Factor and of HIV Replication in Patients With AIDS Completed Hoechst Marion Roussel Phase 1 1969-12-31 To determine whether pentoxifylline lowers tumor necrosis factor (TNF) levels in AIDS patients. Pentoxifylline decreases tumor necrosis factor (TNF), and therefore should decrease such TNF-intensified events as cachexia, enhanced HIV expression, and inhibition of zidovudine (AZT) activity.
NCT00000646 Pentoxifylline (Trental) as a Modulator of Tumor Necrosis Factor and of HIV Replication in Patients With AIDS Completed National Institute of Allergy and Infectious Diseases (NIAID) Phase 1 1969-12-31 To determine whether pentoxifylline lowers tumor necrosis factor (TNF) levels in AIDS patients. Pentoxifylline decreases tumor necrosis factor (TNF), and therefore should decrease such TNF-intensified events as cachexia, enhanced HIV expression, and inhibition of zidovudine (AZT) activity.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Pentoxifylline

Condition Name

Condition Name for Pentoxifylline
Intervention Trials
Alcoholic Hepatitis 7
Fibrosis 3
Cardiovascular Diseases 3
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Condition MeSH

Condition MeSH for Pentoxifylline
Intervention Trials
Kidney Diseases 11
Hepatitis, Alcoholic 10
Hepatitis A 10
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Clinical Trial Locations for Pentoxifylline

Trials by Country

Trials by Country for Pentoxifylline
Location Trials
United States 76
Egypt 5
Taiwan 5
United Kingdom 4
France 4
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Trials by US State

Trials by US State for Pentoxifylline
Location Trials
Texas 8
Minnesota 5
Illinois 5
Ohio 5
Missouri 4
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Clinical Trial Progress for Pentoxifylline

Clinical Trial Phase

Clinical Trial Phase for Pentoxifylline
Clinical Trial Phase Trials
Phase 4 16
Phase 3 20
Phase 2/Phase 3 7
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Clinical Trial Status

Clinical Trial Status for Pentoxifylline
Clinical Trial Phase Trials
Completed 40
Recruiting 18
Not yet recruiting 16
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Clinical Trial Sponsors for Pentoxifylline

Sponsor Name

Sponsor Name for Pentoxifylline
Sponsor Trials
National Taiwan University Hospital 5
National Heart, Lung, and Blood Institute (NHLBI) 5
National Cancer Institute (NCI) 4
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Sponsor Type

Sponsor Type for Pentoxifylline
Sponsor Trials
Other 142
NIH 16
Industry 10
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