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Generated: December 11, 2018

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CLINICAL TRIALS PROFILE FOR PENICILLAMINE

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Clinical Trials for Penicillamine

Trial ID Title Status Sponsor Phase Summary
NCT00003751 Penicillamine, Low Copper Diet, and Radiation Therapy in Treating Patients With Glioblastoma Completed National Cancer Institute (NCI) Phase 2 RATIONALE: Penicillamine may stop the growth of glioblastomas by stopping blood flow to the tumor. A diet low in copper may interfere with the growth of brain tumor cells. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining these therapies may be effective in treating glioblastoma. PURPOSE: Phase II trial to study the effectiveness of penicillamine, a low copper diet, and radiation therapy in treating patients who have newly diagnosed glioblastoma.
NCT00003751 Penicillamine, Low Copper Diet, and Radiation Therapy in Treating Patients With Glioblastoma Completed Sidney Kimmel Comprehensive Cancer Center Phase 2 RATIONALE: Penicillamine may stop the growth of glioblastomas by stopping blood flow to the tumor. A diet low in copper may interfere with the growth of brain tumor cells. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining these therapies may be effective in treating glioblastoma. PURPOSE: Phase II trial to study the effectiveness of penicillamine, a low copper diet, and radiation therapy in treating patients who have newly diagnosed glioblastoma.
NCT00161148 Probiotics in Patients With Primary Sclerosing Cholangitis Unknown status UMC Utrecht Phase 3 PSC is a progressive liver disease without effective medical treatment. There is often co-existent ulcerative colitis. Probiotics (bacterial food supplements) have been shown to benefit patients with ulcerative colitis. In the current protocol potential beneficial effects of probiotics on liver biochemistry and liver related symptoms as pruritus are being assessed in 12 PSC patients in a randomized controlled cross over study (3 months probiotics, 1 one wash-out and 3 months placebo).
NCT00212355 Efficacy and Safety, Long-term Study of Zinc Acetate to Treat Wilson's Disease in Japan. Completed Nobelpharma Phase 3 The purpose of this long-term study is to determine whether Zinc Acetate is effective and safe in the treatment of Wilson's disease among Japanese.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Penicillamine

Condition Name

Condition Name for Penicillamine
Intervention Trials
Wilson Disease 4
Scleroderma 2
Arthritis, Rheumatoid 1
Rheumatoid Arthritis 1
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Condition MeSH

Condition MeSH for Penicillamine
Intervention Trials
Hepatolenticular Degeneration 5
Arthritis, Rheumatoid 2
Arthritis 2
Lead Poisoning 1
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Clinical Trial Locations for Penicillamine

Trials by Country

Trials by Country for Penicillamine
Location Trials
United States 33
United Kingdom 4
Germany 3
Poland 3
Netherlands 2
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Trials by US State

Trials by US State for Penicillamine
Location Trials
Pennsylvania 3
Connecticut 3
New York 2
California 2
Texas 2
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Clinical Trial Progress for Penicillamine

Clinical Trial Phase

Clinical Trial Phase for Penicillamine
Clinical Trial Phase Trials
Phase 4 2
Phase 3 4
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Penicillamine
Clinical Trial Phase Trials
Completed 6
Active, not recruiting 3
Recruiting 2
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Clinical Trial Sponsors for Penicillamine

Sponsor Name

Sponsor Name for Penicillamine
Sponsor Trials
University of Pennsylvania 1
Wilson Therapeutics AB 1
Nobelpharma 1
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Sponsor Type

Sponsor Type for Penicillamine
Sponsor Trials
Industry 10
Other 6
NIH 2
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Serving hundreds of leading biopharmaceutical companies globally:

Accenture
Farmers Insurance
Johnson and Johnson
Chinese Patent Office
Chubb
Covington
McKinsey
Mallinckrodt
Merck

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