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Generated: December 15, 2018

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CLINICAL TRIALS PROFILE FOR PEMETREXED DISODIUM

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Clinical Trials for Pemetrexed Disodium

Trial ID Title Status Sponsor Phase Summary
NCT00003711 Combination Chemotherapy in Treating Patients With Metastatic Solid Tumors Completed San Antonio Cancer Institute Phase 1 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy with pemetrexed disodium and irinotecan in treating patients who have metastatic solid tumors.
NCT00005636 Cisplatin With or Without Pemetrexed Disodium in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot be Removed by Surgery Completed National Cancer Institute (NCI) Phase 3 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if cisplatin is more effective with or without pemetrexed disodium for malignant mesothelioma of the pleura. PURPOSE: Randomized phase III trial to compare the effectiveness of cisplatin with or without pemetrexed disodium in treating patients who have malignant mesothelioma of the pleura that cannot be removed by surgery.
NCT00005636 Cisplatin With or Without Pemetrexed Disodium in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot be Removed by Surgery Completed Memorial Sloan Kettering Cancer Center Phase 3 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if cisplatin is more effective with or without pemetrexed disodium for malignant mesothelioma of the pleura. PURPOSE: Randomized phase III trial to compare the effectiveness of cisplatin with or without pemetrexed disodium in treating patients who have malignant mesothelioma of the pleura that cannot be removed by surgery.
NCT00006007 LY231514 Plus Gemcitabine in Treating Women With Metastatic Breast Cancer Completed National Cancer Institute (NCI) Phase 2 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining LY231514 plus gemcitabine in treating women who have metastatic breast cancer.
NCT00006007 LY231514 Plus Gemcitabine in Treating Women With Metastatic Breast Cancer Completed Alliance for Clinical Trials in Oncology Phase 2 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining LY231514 plus gemcitabine in treating women who have metastatic breast cancer.
NCT00022646 Pemetrexed Disodium Plus Gemcitabine in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Completed National Cancer Institute (NCI) Phase 2 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving more than one drug and giving the drugs in different ways may kill more tumor cells. PURPOSE: Randomized phase II trial to compare the effectiveness of three different regimens of pemetrexed disodium plus gemcitabine in treating patients who have locally advanced or metastatic non-small cell lung cancer.
NCT00022646 Pemetrexed Disodium Plus Gemcitabine in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Completed Alliance for Clinical Trials in Oncology Phase 2 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving more than one drug and giving the drugs in different ways may kill more tumor cells. PURPOSE: Randomized phase II trial to compare the effectiveness of three different regimens of pemetrexed disodium plus gemcitabine in treating patients who have locally advanced or metastatic non-small cell lung cancer.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Pemetrexed Disodium

Condition Name

Condition Name for Pemetrexed Disodium
Intervention Trials
Lung Cancer 28
Stage IV Non-small Cell Lung Cancer 13
Unspecified Adult Solid Tumor, Protocol Specific 8
Recurrent Non-small Cell Lung Cancer 7
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Condition MeSH

Condition MeSH for Pemetrexed Disodium
Intervention Trials
Lung Neoplasms 55
Carcinoma, Non-Small-Cell Lung 43
Mesothelioma 11
Adenocarcinoma 7
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Clinical Trial Locations for Pemetrexed Disodium

Trials by Country

Trials by Country for Pemetrexed Disodium
Location Trials
United States 676
Canada 12
Spain 5
Ireland 5
China 4
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Trials by US State

Trials by US State for Pemetrexed Disodium
Location Trials
Ohio 31
Michigan 30
Illinois 29
California 28
North Carolina 28
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Clinical Trial Progress for Pemetrexed Disodium

Clinical Trial Phase

Clinical Trial Phase for Pemetrexed Disodium
Clinical Trial Phase Trials
Phase 4 1
Phase 3 8
Phase 2 51
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Clinical Trial Status

Clinical Trial Status for Pemetrexed Disodium
Clinical Trial Phase Trials
Completed 44
Active, not recruiting 16
Terminated 12
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Clinical Trial Sponsors for Pemetrexed Disodium

Sponsor Name

Sponsor Name for Pemetrexed Disodium
Sponsor Trials
National Cancer Institute (NCI) 70
Alliance for Clinical Trials in Oncology 12
Gynecologic Oncology Group 7
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Sponsor Type

Sponsor Type for Pemetrexed Disodium
Sponsor Trials
Other 88
NIH 70
Industry 8
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Serving hundreds of leading biopharmaceutical companies globally:

Cantor Fitzgerald
Teva
McKesson
Daiichi Sankyo
Chubb
Mallinckrodt
Covington
Fuji
Merck

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