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Last Updated: March 28, 2024

CLINICAL TRIALS PROFILE FOR PAMIDRONATE DISODIUM


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All Clinical Trials for Pamidronate Disodium

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00004088 ↗ Combination Chemo, Peripheral Stem Cell Transplant, Biological Therapy, Pamidronate and Thalidomide for Multiple Myeloma Completed National Cancer Institute (NCI) Phase 2 1999-04-13 RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow doctors to give higher doses of chemotherapy drugs and kill more cancer cells. Biological therapies, such as interferon alfa, use different ways to stimulate the immune system and stop cancer cells from growing. Thalidomide may stop the growth of cancer cells by stopping blood flow to the tumor. Pamidronate may help to reduce the side effects of treatment for multiple myeloma. PURPOSE: This phase II trial is studying combination chemotherapy, peripheral stem cell transplantation, biological therapy, pamidronate, and thalidomide to see how well they work in treating patients with stage I, stage II, or stage III multiple myeloma.
NCT00004088 ↗ Combination Chemo, Peripheral Stem Cell Transplant, Biological Therapy, Pamidronate and Thalidomide for Multiple Myeloma Completed City of Hope Medical Center Phase 2 1999-04-13 RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow doctors to give higher doses of chemotherapy drugs and kill more cancer cells. Biological therapies, such as interferon alfa, use different ways to stimulate the immune system and stop cancer cells from growing. Thalidomide may stop the growth of cancer cells by stopping blood flow to the tumor. Pamidronate may help to reduce the side effects of treatment for multiple myeloma. PURPOSE: This phase II trial is studying combination chemotherapy, peripheral stem cell transplantation, biological therapy, pamidronate, and thalidomide to see how well they work in treating patients with stage I, stage II, or stage III multiple myeloma.
NCT00004906 ↗ Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Metastatic Breast Cancer Completed National Cancer Institute (NCI) Phase 2 1999-10-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus peripheral stem cell transplantation in treating women who have metastatic breast cancer.
NCT00004906 ↗ Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Metastatic Breast Cancer Completed Hackensack Meridian Health Phase 2 1999-10-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus peripheral stem cell transplantation in treating women who have metastatic breast cancer.
NCT00004906 ↗ Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Metastatic Breast Cancer Completed Hackensack University Medical Center Phase 2 1999-10-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus peripheral stem cell transplantation in treating women who have metastatic breast cancer.
NCT00033332 ↗ Dexamethasone With or Without Thalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma Completed National Cancer Institute (NCI) Phase 3 2002-04-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Thalidomide may stop the growth of cancer by stopping blood flow to the tumor. Combining dexamethasone and thalidomide may kill more cancer cells. It is not yet known whether dexamethasone is more effective with or without thalidomide in treating multiple myeloma. PURPOSE: Randomized phase III trial to determine the effectiveness of dexamethasone with or without thalidomide in treating patients who have multiple myeloma.
NCT00124605 ↗ Arsenic Trioxide and Pamidronate in Treating Patients With Advanced Solid Tumors or Multiple Myeloma Completed National Cancer Institute (NCI) Phase 1 2005-04-01 Drugs used in chemotherapy, such as arsenic trioxide and pamidronate, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Arsenic trioxide and pamidronate may also stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Pamidronate may also stop the growth of cancer cells by blocking blood flow to the cancer. Giving arsenic trioxide together with pamidronate may kill more cancer cells. This phase I trial is studying the side effects and best dose of arsenic trioxide and pamidronate in treating patients with advanced solid tumors or multiple myeloma
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Pamidronate Disodium

Condition Name

Condition Name for Pamidronate Disodium
Intervention Trials
Multiple Myeloma and Plasma Cell Neoplasm 3
Breast Cancer 1
Femoral Head Avascular Necrosis 1
Pain 1
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Condition MeSH

Condition MeSH for Pamidronate Disodium
Intervention Trials
Multiple Myeloma 4
Neoplasms, Plasma Cell 4
Plasmacytoma 3
Femur Head Necrosis 1
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Clinical Trial Locations for Pamidronate Disodium

Trials by Country

Trials by Country for Pamidronate Disodium
Location Trials
United States 36
Spain 1
South Africa 1
Puerto Rico 1
Canada 1
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Trials by US State

Trials by US State for Pamidronate Disodium
Location Trials
California 3
Illinois 2
Arizona 2
Minnesota 2
Pennsylvania 2
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Clinical Trial Progress for Pamidronate Disodium

Clinical Trial Phase

Clinical Trial Phase for Pamidronate Disodium
Clinical Trial Phase Trials
Phase 4 1
Phase 3 1
Phase 2 2
[disabled in preview] 4
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Clinical Trial Status

Clinical Trial Status for Pamidronate Disodium
Clinical Trial Phase Trials
Completed 7
Terminated 1
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Clinical Trial Sponsors for Pamidronate Disodium

Sponsor Name

Sponsor Name for Pamidronate Disodium
Sponsor Trials
National Cancer Institute (NCI) 5
City of Hope Medical Center 1
Hackensack Meridian Health 1
[disabled in preview] 4
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Sponsor Type

Sponsor Type for Pamidronate Disodium
Sponsor Trials
Other 7
NIH 5
Industry 1
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