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Generated: December 14, 2018

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CLINICAL TRIALS PROFILE FOR OXYCODONE

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Clinical Trials for Oxycodone

Trial ID Title Status Sponsor Phase Summary
NCT00000273 A Laboratory Model for Heroin Abuse Medications - 8 Completed National Institute on Drug Abuse (NIDA) Phase 2 The purpose of this study is to evaluate the effects of treatment medications (methadone, buprenorphine, LAAM, naltrexone, naltrexone microcapsules, and methoclocinnamox) on I.V. and smoked heroin self-administration."
NCT00000273 A Laboratory Model for Heroin Abuse Medications - 8 Completed New York State Psychiatric Institute Phase 2 The purpose of this study is to evaluate the effects of treatment medications (methadone, buprenorphine, LAAM, naltrexone, naltrexone microcapsules, and methoclocinnamox) on I.V. and smoked heroin self-administration."
NCT00027014 Herb-Opioid Interactions Completed National Center for Complementary and Integrative Health (NCCIH) Phase 4 This is a series of studies in healthy volunteers to assess the potential for adverse interactions between St. John's wort (SJW) extract and two narcotic (opioid) pain medications: oxycodone and fentanyl. In the case of oxycodone, we are interested in whether SJW treatment promotes the metabolism of oxycodone, such that it lowers the effectiveness of standard doses of oxycodone in treating pain problems. For the fentanyl study, we will investigate whether SJW treatment will interfere with the delivery of fentanyl to the brain and diminish it's effectiveness to relieve pain. There is evidence to suggest that SJW treatment may increase the activity of a transporter protein, named P-glycoprotein (Pgp), in the blood-brain barrier (BBB) that protects the brain from exposure to drugs and other dietary and environmental toxins.
NCT00092313 A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-182) Completed Merck Sharp & Dohme Corp. Phase 3 The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.
NCT00092326 A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-183) Completed Merck Sharp & Dohme Corp. Phase 3 The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.
NCT00158184 Prescription Opioid Effects in Abusers Versus Non-Abusers Completed National Institute on Drug Abuse (NIDA) Phase 2 The purpose of this study is to examine the abuse liability of oxycodone and codeine in individuals with, and without, a history of prescription opioid abuse. The subjective and reinforcing effects of each drug will also be examined in the presence, and absence, of experimentally induced pain.
NCT00158184 Prescription Opioid Effects in Abusers Versus Non-Abusers Completed New York State Psychiatric Institute Phase 2 The purpose of this study is to examine the abuse liability of oxycodone and codeine in individuals with, and without, a history of prescription opioid abuse. The subjective and reinforcing effects of each drug will also be examined in the presence, and absence, of experimentally induced pain.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Oxycodone

Condition Name

Condition Name for Oxycodone
Intervention Trials
Pain 75
Postoperative Pain 30
Healthy 29
Pain, Postoperative 27
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Condition MeSH

Condition MeSH for Oxycodone
Intervention Trials
Pain, Postoperative 82
Back Pain 27
Osteoarthritis 26
Low Back Pain 24
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Clinical Trial Locations for Oxycodone

Trials by Country

Trials by Country for Oxycodone
Location Trials
United States 868
China 27
Canada 21
Finland 18
Italy 17
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Trials by US State

Trials by US State for Oxycodone
Location Trials
New York 58
California 49
Texas 48
Pennsylvania 44
Florida 35
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Clinical Trial Progress for Oxycodone

Clinical Trial Phase

Clinical Trial Phase for Oxycodone
Clinical Trial Phase Trials
Phase 4 127
Phase 3 96
Phase 2/Phase 3 3
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Clinical Trial Status

Clinical Trial Status for Oxycodone
Clinical Trial Phase Trials
Completed 209
Recruiting 67
Not yet recruiting 50
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Clinical Trial Sponsors for Oxycodone

Sponsor Name

Sponsor Name for Oxycodone
Sponsor Trials
Purdue Pharma LP 23
Grünenthal GmbH 18
Pfizer 17
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Sponsor Type

Sponsor Type for Oxycodone
Sponsor Trials
Other 278
Industry 205
NIH 21
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UBS
Colorcon
Federal Trade Commission
Express Scripts

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