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Generated: June 26, 2019

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CLINICAL TRIALS PROFILE FOR ORABASE HCA

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Clinical Trials for Orabase Hca

Trial ID Title Status Sponsor Phase Summary
NCT02329600 Evaluation of Green Tea as Antioxidant Agent in Management of Oral Lichen Planus Completed Cairo University Phase 3 The study included forty individuals divided into 3 groups. 10 control subjects, 15 oral lichen planus (OLP) patients who were treated with topical corticosteroids and 15 oral lichen planus (OLP) patients who were treated with topical corticosteroids and green tea tablets.
NCT02645656 Topical Application of Curcumin Orabase in Oral Submucous Fibrosis (OSMF) Active, not recruiting SVS Institute of Dental Sciences Phase 2 Curcumin (diferuloylmethane) is the chief component of the spice turmeric and is derived from the rhizome of the East Indian plant Curcuma longa. Curcuma longais a member of the Zingiberacae (ginger) family of botanicals and is a perennial plant that is native to Southeast Asia. Turmeric contains a class of compounds known as the curcuminoids, comprised of curcumin, demethoxy curcumin and bisdemethoxycurcumin.
NCT03026478 Topical Betamethasone and Clobetasol in Orabase in Oral Lichen Planus Recruiting Garlapati Komali Phase 2 Oral Lichen Planus (OLP) is an autoimmune, chronic inflammatory mucocutaneous disease characterized by pain and burning sensation. The major types of OLP are the following: reticular, atrophic, erosive-ulcerative, bullous and pigmentous form.Its etiology remains unclear. The presence of auto-cytotoxic T cell clones in the lesions suggests the role of autoimmunity. Numerous treatment options of OLP include topical and systemic agents depending on severity of lesions . Topical corticosteroids abide the mainstay of therapy,and are widely accepted as the primary treatment of choice.Hence this study is designed to evaluate and compare the clinical efficacy of topical Clobetasol 0.05% in orabase and Betamethasone 0.05% in orabase in combination with Clotrimazole 1% in the management of symptomatic Oral Lichen Planus.
NCT03415165 Efficacy of Green Tea Buccal Tablets in Oral Lichen Planus Recruiting Cairo University Early Phase 1 Is topical application of green tea polyphenols buccal tablet more effective in treatment of patients with symptomatic oral lichen planus in comparison with topical application of corticosteroids and what is the most effective concentration of polyphenols
NCT03572959 Management of Pain in Oral Lichen Planus Completed Sherine Adel Nasry Phase 4 Treating Oral Lichen Planus (OLP) is a big challenge for clinicians. Despite numerous existing remedies, to date no effective cure has been found, which is mainly attributed to the lack of understanding of the pathogenesis of the disease. The investigator's aim was comparing the effectiveness of topical steroids and diode laser in treating OLP patients. Twenty-four patients with OLP were allocated into two groups of twelve patients each. One group was treated with 970 nm diode laser applied twice weekly and the other group was treated with topical steroids applied four times per day. Patients were followed up for two months. Pain was recorded using the visual analog score (VAS) and the clinical signs and symptoms were recorded using the reticular, atrophic, erosive (RAE) sores. Pain and RAE records were taken before treatment, after treatment and after 2 months.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Orabase Hca

Condition Name

Condition Name for Orabase Hca
Intervention Trials
Oral Lichen Planus 5
Behcet Syndrome 1
Autoimmune 1
Oral Ulcer Due to Steven Johnson's Syndrome 1
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Condition MeSH

Condition MeSH for Orabase Hca
Intervention Trials
Lichen Planus, Oral 5
Lichen Planus 5
Oral Ulcer 2
Behcet Syndrome 1
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Clinical Trial Locations for Orabase Hca

Trials by Country

Trials by Country for Orabase Hca
Location Trials
India 2
Egypt 1
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Clinical Trial Progress for Orabase Hca

Clinical Trial Phase

Clinical Trial Phase for Orabase Hca
Clinical Trial Phase Trials
Phase 4 1
Phase 3 1
Phase 2 2
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Clinical Trial Status

Clinical Trial Status for Orabase Hca
Clinical Trial Phase Trials
Not yet recruiting 3
Completed 2
Recruiting 2
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Clinical Trial Sponsors for Orabase Hca

Sponsor Name

Sponsor Name for Orabase Hca
Sponsor Trials
Cairo University 3
Beni-Suef University 1
Mona Taha Mohammed MD 1
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Sponsor Type

Sponsor Type for Orabase Hca
Sponsor Trials
Other 8
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