CLINICAL TRIALS PROFILE FOR ORABASE HCA
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All Clinical Trials for Orabase Hca
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT02329600 ↗ | Evaluation of Green Tea as Antioxidant Agent in Management of Oral Lichen Planus | Completed | Cairo University | Phase 3 | 2013-06-01 | The study included forty individuals divided into 3 groups. 10 control subjects, 15 oral lichen planus (OLP) patients who were treated with topical corticosteroids and 15 oral lichen planus (OLP) patients who were treated with topical corticosteroids and green tea tablets. |
| NCT02645656 ↗ | Topical Application of Curcumin Orabase in Oral Submucous Fibrosis (OSMF) | Unknown status | SVS Institute of Dental Sciences | Phase 2 | 2013-12-01 | Curcumin (diferuloylmethane) is the chief component of the spice turmeric and is derived from the rhizome of the East Indian plant Curcuma longa. Curcuma longais a member of the Zingiberacae (ginger) family of botanicals and is a perennial plant that is native to Southeast Asia. Turmeric contains a class of compounds known as the curcuminoids, comprised of curcumin, demethoxy curcumin and bisdemethoxycurcumin. |
| NCT03026478 ↗ | Topical Betamethasone and Clobetasol in Orabase in Oral Lichen Planus | Unknown status | Garlapati Komali | Phase 2 | 2016-05-06 | Oral Lichen Planus (OLP) is an autoimmune, chronic inflammatory mucocutaneous disease characterized by pain and burning sensation. The major types of OLP are the following: reticular, atrophic, erosive-ulcerative, bullous and pigmentous form.Its etiology remains unclear. The presence of auto-cytotoxic T cell clones in the lesions suggests the role of autoimmunity. Numerous treatment options of OLP include topical and systemic agents depending on severity of lesions . Topical corticosteroids abide the mainstay of therapy,and are widely accepted as the primary treatment of choice.Hence this study is designed to evaluate and compare the clinical efficacy of topical Clobetasol 0.05% in orabase and Betamethasone 0.05% in orabase in combination with Clotrimazole 1% in the management of symptomatic Oral Lichen Planus. |
| NCT03415165 ↗ | Efficacy of Green Tea Buccal Tablets in Oral Lichen Planus | Unknown status | Cairo University | Early Phase 1 | 2018-01-03 | Is topical application of green tea polyphenols buccal tablet more effective in treatment of patients with symptomatic oral lichen planus in comparison with topical application of corticosteroids and what is the most effective concentration of polyphenols |
| NCT03572959 ↗ | Management of Pain in Oral Lichen Planus | Completed | Sherine Adel Nasry | Phase 4 | 2016-12-27 | Treating Oral Lichen Planus (OLP) is a big challenge for clinicians. Despite numerous existing remedies, to date no effective cure has been found, which is mainly attributed to the lack of understanding of the pathogenesis of the disease. The investigator's aim was comparing the effectiveness of topical steroids and diode laser in treating OLP patients. Twenty-four patients with OLP were allocated into two groups of twelve patients each. One group was treated with 970 nm diode laser applied twice weekly and the other group was treated with topical steroids applied four times per day. Patients were followed up for two months. Pain was recorded using the visual analog score (VAS) and the clinical signs and symptoms were recorded using the reticular, atrophic, erosive (RAE) sores. Pain and RAE records were taken before treatment, after treatment and after 2 months. |
| NCT03738176 ↗ | The Efficacy of Topical Sesame Oil Versus Topical Triamcinolone on Oral Lichen Planus and Salivary Level of Oxidative Stress Biomarker [MDA] | Unknown status | Mona Taha Mohammed MD | Early Phase 1 | 2019-12-16 | use seseme oil and corticosteroid topically for two groups |
| NCT03771768 ↗ | Diode Laser Versus Topical Corticosteroids in Management of Oral Ulcers in Behcet's Disease | Unknown status | Cairo University | N/A | 2019-05-25 | Laser therapy is increasingly showing promising results in dental field including oral ulcers.This trial will assess the usefulness of Diode Laser compared to corticosteroid on oral ulcers of patients diagnosed with Behcet's disease. |
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