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Last Updated: March 26, 2023

CLINICAL TRIALS PROFILE FOR OMACETAXINE MEPESUCCINATE

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All Clinical Trials for Omacetaxine Mepesuccinate

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00002574 ↗	Homoharringtonine and Interferon Alfa in Treating Patients With Chronic Myelogenous Leukemia	Completed	National Cancer Institute (NCI)	Phase 2	1994-09-01	Phase II trial to study the effectiveness of homoharringtonine and interferon alfa in treating patients with chronic myelogenous leukemia. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Interferon alfa may interfere with the growth of cancer cells. Combining chemotherapy with interferon alfa may kill more cancer cells.
NCT00003239 ↗	Chemotherapy and Biological Therapy in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia	Completed	National Cancer Institute (NCI)	Phase 2	1998-03-01	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining biological therapy with chemotherapy may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of chemotherapy with cytarabine and homoharringtonine and biological therapy with interferon alfa in treating patients with chronic phase chronic myelogenous leukemia.
NCT00003239 ↗	Chemotherapy and Biological Therapy in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia	Completed	M.D. Anderson Cancer Center	Phase 2	1998-03-01	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining biological therapy with chemotherapy may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of chemotherapy with cytarabine and homoharringtonine and biological therapy with interferon alfa in treating patients with chronic phase chronic myelogenous leukemia.
NCT00003694 ↗	Homoharringtonine Plus Low-Dose Cytarabine in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia in Chronic Phase	Completed	National Cancer Institute (NCI)	Phase 2	1999-03-01	Phase II trial to study the effectiveness of homoharringtonine plus low-dose cytarabine in treating patients who have newly diagnosed chronic phase chronic myelogenous leukemia. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
NCT00006364 ↗	Homoharringtonine in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia	Completed	National Cancer Institute (NCI)	Phase 2	1999-11-01	Phase II trial to study the effectiveness of homoharringtonine in treating patients who have chronic phase chronic myelogenous leukemia. Drugs used in chemotherapy, such as homoharringtonine, work in different ways to stop cancer cells from dividing so they stop growing or die
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for Omacetaxine Mepesuccinate

Condition Name

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Condition Name for Omacetaxine Mepesuccinate
Intervention	Trials
Chronic Myeloid Leukemia	3
Chronic Myelogenous Leukemia, BCR-ABL1 Positive	2
Chronic Phase Chronic Myelogenous Leukemia	2
FLT3-ITD Mutation	2
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Condition MeSH

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Condition MeSH for Omacetaxine Mepesuccinate
Intervention	Trials
Leukemia	10
Leukemia, Myeloid	10
Leukemia, Myelogenous, Chronic, BCR-ABL Positive	8
Leukemia, Myeloid, Chronic-Phase	4
[disabled in preview]	0
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Clinical Trial Locations for Omacetaxine Mepesuccinate

Trials by Country

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Trials by Country for Omacetaxine Mepesuccinate
Location	Trials
United States	33
France	3
Hungary	2
Poland	2
Hong Kong	2
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Trials by US State

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Trials by US State for Omacetaxine Mepesuccinate
Location	Trials
Texas	9
New York	4
Indiana	3
Massachusetts	3
Pennsylvania	2
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Clinical Trial Progress for Omacetaxine Mepesuccinate

Clinical Trial Phase

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Clinical Trial Phase for Omacetaxine Mepesuccinate
Clinical Trial Phase	Trials
Phase 2	10
Phase 1/Phase 2	4
Phase 1	2
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Clinical Trial Status

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Clinical Trial Status for Omacetaxine Mepesuccinate
Clinical Trial Phase	Trials
Completed	9
Terminated	4
Recruiting	1
[disabled in preview]	2
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Clinical Trial Sponsors for Omacetaxine Mepesuccinate

Sponsor Name

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Sponsor Name for Omacetaxine Mepesuccinate
Sponsor	Trials
National Cancer Institute (NCI)	5
ChemGenex Pharmaceuticals	4
Teva Branded Pharmaceutical Products R&D, Inc.	4
[disabled in preview]	5
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Sponsor Type

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Sponsor Type for Omacetaxine Mepesuccinate
Sponsor	Trials
Industry	16
Other	7
NIH	5
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