Effectiveness and Safety of Epivir/Ziagen/Zerit (3TC/ABC/d4T) Versus Epivir/Ziagen/Sustiva (3TC/ABC/EFV) Versus Epivir/Ziagen/Agenerase/Norvir (3TC/ABC/APV/RTV) in HIV Patients Who Have Never Received Treatment
Unknown status
Glaxo Wellcome
Phase 4
1969-12-31
The purpose of this study is to see how effective and safe it is to give 1 of the 3 following
treatments to patients who may not have received anti-HIV treatment: 1) lamivudine
(3TC)/abacavir (ABC)/stavudine (d4T); 2) 3TC/ABC/efavirenz (EFV); or 3) 3TC/ABC/amprenavir
(APV)/ritonavir (RTV).
Effect of an Enfuvirtide-based Anti-HIV Drug Regimen on Latent HIV Reservoirs in Treatment Naive Adults
Completed
AIDS Clinical Trials Group
N/A
2003-10-01
HIV replication in resting CD4 cells is so minimal that anti-HIV drugs often fail to destroy
the virus in these cells. Enfuvirtide, also known as T-20, is a type of anti-HIV drug called
a fusion inhibitor. The purpose of this study is to test the ability of a T-20-enhanced
treatment regimen to decrease the number of resting CD4 cells that become infected with HIV.
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