A Study to Evaluate the Effect of Nandrolone Decanoate in Women With HIV-Associated Weight Loss
National Institute of Allergy and Infectious Diseases (NIAID)
The purpose of this study is to see if giving nandrolone decanoate (a hormonal drug) will
cause weight gain in HIV-positive women who have HIV-associated weight loss (wasting).
Wasting has become an AIDS-defining condition. In the past, most studies that examined
wasting treatments were limited to men. However, it appears that wasting in HIV-positive men
is linked to levels of testosterone (a hormone which affects men's bodies more than
women's). This study has been designed for women only, in order to best treat wasting in
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