Oral Anti-Infective Agent for Esophageal Anastomotic Leakage
Unknown status
National Taiwan University Hospital
Phase 2
2009-06-01
Anastomotic leakage is still to be a major cause of considerable morbidity and mortality
after esophagectomy and gastric pull up for esophageal carcinoma. Risk factor analyses of
anastomotic leakage, including blood supply, graft tension, and comorbidity, have been
performed, but few studies have produced strategies that have improved operative results.
This study will be performed to identify prognostic variables that might be used to develop a
strategy for optimizing outcomes after esophagogastrectomy.
Antifungal Prophylaxis in Intensive Care Unit (ICU) Patients
Completed
Policlinico Hospital
Phase 4
2008-11-01
Purpose. Oral chemoprophylaxis has been advocated to reduce the incidence of Candida
colonization and infection. However, Candida prophylaxis in intensive care unit (ICU) is
still a matter of debate.
Methods. Randomized, single-center trial studying single drug (nystatin) versus control in
surgical ICU patients. Multiple-site testing for fungi were performed in each patient at ICU
admission (T0) and subsequently every 3 days (T3, T6, T9…). The primary evaluation criterion
was the time course of colonization index (CI) during ICU stay.
Effects of Denture-Related Stomatitis on Blood Pressure in Denture Wearers
Unknown status
Jagiellonian University
2011-10-01
The aim of this study is to evaluate the influence of presence of oral fungal infection,
which leads to denture-related stomatitis, on blood pressure, endothelial function and immune
cell phenotype in patients wearing dentures.
Oral Nystatin Prophylaxis to Prevent Systemic Fungal Infection in Very Low Birth Weight Preterm Infants
Completed
Dr Cipto Mangunkusumo General Hospital
Phase 4
2010-10-01
This study determines the effectiveness of oral nystatin as prophylaxis in order to prevent
systemic fungal infection in very low birth weight preterm neonates. 47 participants received
oral nystatin and 48 participants received sterile water as part of oral hygiene.
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