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Generated: February 23, 2019

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CLINICAL TRIALS PROFILE FOR MYCOPHENOLIC ACID

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Clinical Trials for Mycophenolic Acid

Trial ID Title Status Sponsor Phase Summary
NCT00007059 Study of the Pharmacokinetics of Mycophenolate Mofetil in Patients Who Have Undergone Orthotopic Liver Transplantation Completed University of North Carolina N/A OBJECTIVES: I. Determine the effects of bile externalization and antibiotic gut sterilization on the pharmacokinetics of mycophenolate mofetil in patients who have undergone orthotopic liver transplantation. II. Correlate serum concentrations of mycophenolic acid with inosine monophosphate dehydrogenase activity in these patients.
NCT00007059 Study of the Pharmacokinetics of Mycophenolate Mofetil in Patients Who Have Undergone Orthotopic Liver Transplantation Completed National Center for Research Resources (NCRR) N/A OBJECTIVES: I. Determine the effects of bile externalization and antibiotic gut sterilization on the pharmacokinetics of mycophenolate mofetil in patients who have undergone orthotopic liver transplantation. II. Correlate serum concentrations of mycophenolic acid with inosine monophosphate dehydrogenase activity in these patients.
NCT00021489 Mycophenolate Mofetil and Abacavir Treatment in HIV Patients With Failed Anti-HIV Treatment Withdrawn National Institute of Allergy and Infectious Diseases (NIAID) Phase 2 The purpose of this study is to learn how safe and well-tolerated mycophenolate mofetil (MMF) is when given with abacavir (ABC). Another purpose is to see if adding MMF to ABC decreases viral load (amount of HIV in the blood) more than ABC alone. Many HIV-infected patients who have had heavy exposure to anti-HIV drugs and have experienced treatment failure need new treatment combinations. One promising combination is ABC and MMF as part of a drug combination. Laboratory studies show that MMF helps ABC destroy HIV in the cells and further clinical testing is needed. MMF is not FDA-approved as a treatment for HIV infection but has been approved by FDA to prevent rejection of organ transplants. Doses of MMF tested in this study will be lower than those used to treat people with organ transplants.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Mycophenolic Acid

Condition Name

Condition Name for Mycophenolic Acid
Intervention Trials
Kidney Transplantation 16
Liver Transplantation 6
Renal Transplantation 5
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Condition MeSH

Condition MeSH for Mycophenolic Acid
Intervention Trials
Renal Insufficiency 6
Nephritis 6
Lupus Nephritis 5
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Clinical Trial Locations for Mycophenolic Acid

Trials by Country

Trials by Country for Mycophenolic Acid
Location Trials
United States 114
Canada 18
Spain 16
Germany 14
France 9
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Trials by US State

Trials by US State for Mycophenolic Acid
Location Trials
California 13
Wisconsin 9
Pennsylvania 7
New York 7
Ohio 7
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Clinical Trial Progress for Mycophenolic Acid

Clinical Trial Phase

Clinical Trial Phase for Mycophenolic Acid
Clinical Trial Phase Trials
Phase 4 43
Phase 3 13
Phase 2/Phase 3 3
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Clinical Trial Status

Clinical Trial Status for Mycophenolic Acid
Clinical Trial Phase Trials
Completed 50
Recruiting 15
Terminated 10
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Clinical Trial Sponsors for Mycophenolic Acid

Sponsor Name

Sponsor Name for Mycophenolic Acid
Sponsor Trials
Novartis Pharmaceuticals 18
Novartis 13
Hoffmann-La Roche 11
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Sponsor Type

Sponsor Type for Mycophenolic Acid
Sponsor Trials
Other 115
Industry 53
NIH 8
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Serving hundreds of leading biopharmaceutical companies globally:

UBS
Argus Health
Daiichi Sankyo
Mallinckrodt
Fish and Richardson
US Army
Citi
Accenture
Teva

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