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CLINICAL TRIALS PROFILE FOR MINIPRESS

Clinical Trials for Minipress

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00161473	Alzheimer's in Long-Term Care--Treatment for Agitation	Completed	National Institute on Aging (NIA)	N/A	2001-01-01	The purpose of this study is to see if a medication called prazosin is useful in the treatment of agitation and aggression in persons with Alzheimer's disease (AD) and other types of dementia in late life.
NCT00161473	Alzheimer's in Long-Term Care--Treatment for Agitation	Completed	University of Washington	N/A	2001-01-01	The purpose of this study is to see if a medication called prazosin is useful in the treatment of agitation and aggression in persons with Alzheimer's disease (AD) and other types of dementia in late life.
NCT00175682	Prazosin Vibrostimulation Autonomic Dysreflexia and Spinal Cord Injury Study	Unknown status	University of British Columbia	N/A	2004-12-01	Sexuality is a high rehabilitative priority for persons following a spinal cord injury (SCI). Sexual acts can lead to autonomic dysreflexia (AD), dangerous consequences such as a sudden increase in blood pressure, severe headache, sweating above the level of the lesion and low heart rate to name a few. Ejaculation in men can provoke these significant symptoms and therefore men and women may refrain from a sexual life and biological parenthood. Adalat is the most common antihypertensive used in fertility clinics to reduce the incidence of AD. It dramatically reduces blood pressure and, therefore, results in side effects such as dizziness, fatigue and weakness. The investigators hypothesize that Minipress® (prazosin HCL), a blood pressure medication, which has a slower and less abrupt suppressive effect on blood pressure, would be a safe, effective and more appropriate medication for use in the outpatient sperm retrieval clinic and potentially for private use.
NCT00183430	Prazosin for Treating Noncombat Trauma Post-Traumatic Stress Disorder	Terminated	National Institute of Mental Health (NIMH)	N/A	2003-10-01	This study will evaluate the effectiveness of prazosin in treating post-traumatic stress disorder caused by noncombat trauma in individuals taking selective serotonin reuptake inhibitors.
NCT00183430	Prazosin for Treating Noncombat Trauma Post-Traumatic Stress Disorder	Terminated	Seattle Institute for Biomedical and Clinical Research	N/A	2003-10-01	This study will evaluate the effectiveness of prazosin in treating post-traumatic stress disorder caused by noncombat trauma in individuals taking selective serotonin reuptake inhibitors.
NCT00202449	Prazosin vs Paroxetine in Combat Stress-Related Post-Traumatic Stress Disorder (PTSD) Nightmares & Sleep Disturbance	Terminated	United States Department of Defense	N/A	2004-07-01	The purposes of this study are: - to evaluate the efficacy and tolerability of the drug prazosin compared to placebo for combat stress-related nightmares, sleep disturbance and overall function in recently combat-exposed returnees from Operation Iraqi Freedom (OIF) and Operation Enduring Freedom (OEF). - to evaluate the effects of the selective serotonin reuptake inhibitor (SSRI) paroxetine on behavioral symptoms and overall function in this population.
NCT00202449	Prazosin vs Paroxetine in Combat Stress-Related Post-Traumatic Stress Disorder (PTSD) Nightmares & Sleep Disturbance	Terminated	VA Puget Sound Health Care System	N/A	2004-07-01	The purposes of this study are: - to evaluate the efficacy and tolerability of the drug prazosin compared to placebo for combat stress-related nightmares, sleep disturbance and overall function in recently combat-exposed returnees from Operation Iraqi Freedom (OIF) and Operation Enduring Freedom (OEF). - to evaluate the effects of the selective serotonin reuptake inhibitor (SSRI) paroxetine on behavioral symptoms and overall function in this population.
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