CLINICAL TRIALS PROFILE FOR MINIPRESS

All Clinical Trials for Minipress

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00161473 ↗	Alzheimer's in Long-Term Care--Treatment for Agitation	Completed	National Institute on Aging (NIA)	N/A	2001-01-01	The purpose of this study is to see if a medication called prazosin is useful in the treatment of agitation and aggression in persons with Alzheimer's disease (AD) and other types of dementia in late life.
NCT00161473 ↗	Alzheimer's in Long-Term Care--Treatment for Agitation	Completed	University of Washington	N/A	2001-01-01	The purpose of this study is to see if a medication called prazosin is useful in the treatment of agitation and aggression in persons with Alzheimer's disease (AD) and other types of dementia in late life.
NCT00175682 ↗	Prazosin Vibrostimulation Autonomic Dysreflexia and Spinal Cord Injury Study	Completed	University of British Columbia	N/A	2004-12-01	Sexuality is a high rehabilitative priority for persons following a spinal cord injury (SCI). Sexual acts can lead to autonomic dysreflexia (AD), dangerous consequences such as a sudden increase in blood pressure, severe headache, sweating above the level of the lesion and low heart rate to name a few. Ejaculation in men can provoke these significant symptoms and therefore men and women may refrain from a sexual life and biological parenthood. Adalat is the most common antihypertensive used in fertility clinics to reduce the incidence of AD. It dramatically reduces blood pressure and, therefore, results in side effects such as dizziness, fatigue and weakness. The investigators hypothesize that Minipress® (prazosin HCL), a blood pressure medication, which has a slower and less abrupt suppressive effect on blood pressure, would be a safe, effective and more appropriate medication for use in the outpatient sperm retrieval clinic and potentially for private use.
NCT00183430 ↗	Prazosin for Treating Noncombat Trauma Post-Traumatic Stress Disorder	Terminated	National Institute of Mental Health (NIMH)	N/A	2003-10-01	This study will evaluate the effectiveness of prazosin in treating post-traumatic stress disorder caused by noncombat trauma in individuals taking selective serotonin reuptake inhibitors.
NCT00183430 ↗	Prazosin for Treating Noncombat Trauma Post-Traumatic Stress Disorder	Terminated	Seattle Institute for Biomedical and Clinical Research	N/A	2003-10-01	This study will evaluate the effectiveness of prazosin in treating post-traumatic stress disorder caused by noncombat trauma in individuals taking selective serotonin reuptake inhibitors.
NCT00202449 ↗	Prazosin vs Paroxetine in Combat Stress-Related Post-Traumatic Stress Disorder (PTSD) Nightmares & Sleep Disturbance	Terminated	United States Department of Defense	N/A	2004-07-01	The purposes of this study are: - to evaluate the efficacy and tolerability of the drug prazosin compared to placebo for combat stress-related nightmares, sleep disturbance and overall function in recently combat-exposed returnees from Operation Iraqi Freedom (OIF) and Operation Enduring Freedom (OEF). - to evaluate the effects of the selective serotonin reuptake inhibitor (SSRI) paroxetine on behavioral symptoms and overall function in this population.
NCT00202449 ↗	Prazosin vs Paroxetine in Combat Stress-Related Post-Traumatic Stress Disorder (PTSD) Nightmares & Sleep Disturbance	Terminated	VA Puget Sound Health Care System	N/A	2004-07-01	The purposes of this study are: - to evaluate the efficacy and tolerability of the drug prazosin compared to placebo for combat stress-related nightmares, sleep disturbance and overall function in recently combat-exposed returnees from Operation Iraqi Freedom (OIF) and Operation Enduring Freedom (OEF). - to evaluate the effects of the selective serotonin reuptake inhibitor (SSRI) paroxetine on behavioral symptoms and overall function in this population.

Clinical Trial Conditions for Minipress

Condition Name

Condition Name for Minipress
Intervention	Trials
Posttraumatic Stress Disorder	5
Alzheimer's Disease	2
Hypertension	2
Stress Disorders, Post-Traumatic	2

Condition MeSH

Condition MeSH for Minipress
Intervention	Trials
Stress Disorders, Post-Traumatic	9
Stress Disorders, Traumatic	7
Disease	7
Alcoholism	6

Clinical Trial Locations for Minipress

Trials by Country

Trials by Country for Minipress
Location	Trials
United States	32
Canada	3

Trials by US State

Trials by US State for Minipress
Location	Trials
Washington	14
Connecticut	3
California	2
Maryland	1
Colorado	1

Clinical Trial Progress for Minipress

Clinical Trial Phase

Clinical Trial Phase for Minipress
Clinical Trial Phase	Trials
Phase 4	4
Phase 3	2
Phase 2	7

Clinical Trial Status

Clinical Trial Status for Minipress
Clinical Trial Phase	Trials
Completed	13
Recruiting	7
Withdrawn	2

Clinical Trial Sponsors for Minipress

Sponsor Name

Sponsor Name for Minipress
Sponsor	Trials
VA Puget Sound Health Care System	7
Seattle Institute for Biomedical and Clinical Research	7
VA Office of Research and Development	4

Sponsor Type

Sponsor Type for Minipress
Sponsor	Trials
Other	29
U.S. Fed	15
NIH	8