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Last Updated: October 14, 2019

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CLINICAL TRIALS PROFILE FOR MEXATE

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Clinical Trials for Mexate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00002798 Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome Completed National Cancer Institute (NCI) Phase 3 1996-08-01 Randomized phase III trial to compare the effectiveness of different chemotherapy regimens with or without bone marrow transplantation in treating children who have acute myelogenous leukemia or myelodysplastic syndrome. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. It is not yet known which treatment regimen is more effective for acute myelogenous leukemia or myelodysplastic syndrome
NCT00002970 506U78 in Treating Patients With Refractory Hematologic Cancer Completed Children's Cancer Group Phase 2 1997-06-01 Phase II trial to study the effectiveness of 506U78 in treating patients with recurrent or refractory hematologic cancer. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
NCT00002970 506U78 in Treating Patients With Refractory Hematologic Cancer Completed National Cancer Institute (NCI) Phase 2 1997-06-01 Phase II trial to study the effectiveness of 506U78 in treating patients with recurrent or refractory hematologic cancer. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
NCT00003702 Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia Completed Eastern Cooperative Oncology Group Phase 3 1999-06-01 Randomized phase III trial to compare the effectiveness of methotrexate with that of dactinomycin in treating patients who have gestational trophoblastic neoplasia. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether methotrexate is more effective than dactinomycin in treating patients with gestational trophoblastic neoplasia.
NCT00003702 Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia Completed National Cancer Institute (NCI) Phase 3 1999-06-01 Randomized phase III trial to compare the effectiveness of methotrexate with that of dactinomycin in treating patients who have gestational trophoblastic neoplasia. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether methotrexate is more effective than dactinomycin in treating patients with gestational trophoblastic neoplasia.
NCT00003702 Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia Completed Gynecologic Oncology Group Phase 3 1999-06-01 Randomized phase III trial to compare the effectiveness of methotrexate with that of dactinomycin in treating patients who have gestational trophoblastic neoplasia. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether methotrexate is more effective than dactinomycin in treating patients with gestational trophoblastic neoplasia.
NCT00003934 Tretinoin, Cytarabine, and Daunorubicin Hydrochloride With or Without Arsenic Trioxide Followed by Tretinoin With or Without Mercaptopurine and Methotrexate in Treating Patients With Acute Promyelocytic Leukemia Completed National Cancer Institute (NCI) Phase 3 1999-06-01 This randomized phase III trial is studying tretinoin and combination chemotherapy to see how well they work compared to tretinoin, combination chemotherapy, and arsenic trioxide in treating patients with acute promyelocytic leukemia that has not been treated previously. Drugs used in chemotherapy, such as daunorubicin, cytarabine, mercaptopurine, methotrexate, and arsenic trioxide, work in different ways to stop cancer cells from dividing so they stop growing or die. Tretinoin may help leukemia cells develop into normal white blood cells. It is not yet known which regimen is more effective for acute promyelocytic leukemia.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Mexate

Condition Name

Condition Name for Mexate
Intervention Trials
Untreated Adult Acute Lymphoblastic Leukemia 16
Recurrent Adult Acute Myeloid Leukemia 13
Untreated Childhood Acute Lymphoblastic Leukemia 13
Adult Acute Myeloid Leukemia in Remission 12
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Condition MeSH

Condition MeSH for Mexate
Intervention Trials
Leukemia 58
Precursor Cell Lymphoblastic Leukemia-Lymphoma 47
Leukemia, Lymphoid 47
Lymphoma 23
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Clinical Trial Locations for Mexate

Trials by Country

Trials by Country for Mexate
Location Trials
Canada 107
Australia 43
New Zealand 17
Japan 8
Puerto Rico 8
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Trials by US State

Trials by US State for Mexate
Location Trials
Washington 38
California 37
Ohio 36
Pennsylvania 35
New York 32
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Clinical Trial Progress for Mexate

Clinical Trial Phase

Clinical Trial Phase for Mexate
Clinical Trial Phase Trials
Phase 4 1
Phase 3 25
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Mexate
Clinical Trial Phase Trials
Completed 27
Recruiting 23
Active, not recruiting 17
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Clinical Trial Sponsors for Mexate

Sponsor Name

Sponsor Name for Mexate
Sponsor Trials
National Cancer Institute (NCI) 73
Children's Oncology Group 16
Fred Hutchinson Cancer Research Center 11
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Sponsor Type

Sponsor Type for Mexate
Sponsor Trials
NIH 81
Other 67
Industry 7
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