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Last Updated: December 15, 2024

CLINICAL TRIALS PROFILE FOR METOPROLOL SUCCINATE


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All Clinical Trials for Metoprolol Succinate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00077948 ↗ Enoximone Plus Extended-Release Metoprolol Succinate in Subjects With Advanced Chronic Heart Failure Terminated AstraZeneca Phase 3 2003-07-01 Beta-blocker medications have been shown to improve heart function and prolong the lives of patients with chronic heart failure (CHF). Some people with advanced CHF have difficulty taking beta-blocker medications due to troublesome side effects, such as low blood pressure and/or low heart rate, severe tiredness, dizziness, or shortness of breath. In other words, they have difficulty tolerating beta-blocker medications. The purpose of this study is to determine if enoximone can improve a patient's ability to tolerate a beta-blocker medication.
NCT00077948 ↗ Enoximone Plus Extended-Release Metoprolol Succinate in Subjects With Advanced Chronic Heart Failure Terminated Gilead Sciences Phase 3 2003-07-01 Beta-blocker medications have been shown to improve heart function and prolong the lives of patients with chronic heart failure (CHF). Some people with advanced CHF have difficulty taking beta-blocker medications due to troublesome side effects, such as low blood pressure and/or low heart rate, severe tiredness, dizziness, or shortness of breath. In other words, they have difficulty tolerating beta-blocker medications. The purpose of this study is to determine if enoximone can improve a patient's ability to tolerate a beta-blocker medication.
NCT00123903 ↗ COREG MR Versus TOPROL-XL On Reduction Of Microalbuminuria In Patients With Hypertension And Microalbuminuria Terminated GlaxoSmithKline Phase 3 2005-07-01 This study was designed to determine whether COREG MR is more effective than TOPROL-XL in reducing microalbuminuria in type 2 diabetic or non-diabetic patients with high blood pressure and microalbuminuria.
NCT00166400 ↗ A Randomized Clinical Trial of Metoprolol in Participants With Mitral Regurgitation. Completed AstraZeneca Phase 4 2004-07-01 Mitral valve regurgitation (leakage of the mitral valve of the heart) is frequent and currently there is no specific medical therapy. Mitral regurgitation is a slowly progressive disease that frequently requires surgical treatment. This randomized clinical trial will use Metoprolol, a common beta-blocker medication, to determine if medical treatment impacts mitral valve disease progression.
NCT00166400 ↗ A Randomized Clinical Trial of Metoprolol in Participants With Mitral Regurgitation. Completed Mayo Clinic Phase 4 2004-07-01 Mitral valve regurgitation (leakage of the mitral valve of the heart) is frequent and currently there is no specific medical therapy. Mitral regurgitation is a slowly progressive disease that frequently requires surgical treatment. This randomized clinical trial will use Metoprolol, a common beta-blocker medication, to determine if medical treatment impacts mitral valve disease progression.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Metoprolol Succinate

Condition Name

Condition Name for Metoprolol Succinate
Intervention Trials
Hypertension 21
Heart Failure 7
Heart Failure With Preserved Ejection Fraction 3
Healthy 3
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Condition MeSH

Condition MeSH for Metoprolol Succinate
Intervention Trials
Hypertension 23
Heart Failure 12
Cardiomyopathies 6
Lung Diseases 2
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Clinical Trial Locations for Metoprolol Succinate

Trials by Country

Trials by Country for Metoprolol Succinate
Location Trials
United States 161
China 28
Canada 17
India 5
Denmark 3
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Trials by US State

Trials by US State for Metoprolol Succinate
Location Trials
New York 11
Pennsylvania 9
Utah 8
Texas 7
Florida 7
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Clinical Trial Progress for Metoprolol Succinate

Clinical Trial Phase

Clinical Trial Phase for Metoprolol Succinate
Clinical Trial Phase Trials
Phase 4 25
Phase 3 14
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Metoprolol Succinate
Clinical Trial Phase Trials
Completed 34
Terminated 9
Not yet recruiting 6
[disabled in preview] 7
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Clinical Trial Sponsors for Metoprolol Succinate

Sponsor Name

Sponsor Name for Metoprolol Succinate
Sponsor Trials
AstraZeneca 10
Forest Laboratories 7
GlaxoSmithKline 5
[disabled in preview] 6
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Sponsor Type

Sponsor Type for Metoprolol Succinate
Sponsor Trials
Other 74
Industry 41
NIH 3
[disabled in preview] 3
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