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Last Updated: January 27, 2023

CLINICAL TRIALS PROFILE FOR MELPHALAN FLUFENAMIDE HYDROCHLORIDE


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All Clinical Trials for Melphalan Flufenamide Hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01897714 ↗ Safety and Efficacy of Melflufen and Dexamethasone in Relapsed and/or Relapsed-Refractory Multiple Myeloma Patients Terminated Oncopeptides AB Phase 1/Phase 2 2013-07-01 The study will explore escalating doses of melflufen in combination with dexamethasone in small groups of patients to find the maximum tolerated dose of melflufen. That dose will then be used to determine the efficacy and safety profile of melflufen in combination with dexamethasone in a larger group of patients.
NCT02963493 ↗ A Study of Melphalan Flufenamide (Melflufen) in Combination With Dexamethasone in Relapsed Refractory Multiple Myeloma Patients Active, not recruiting Precision For Medicine Phase 2 2016-12-28 This study will evaluate melflufen in combination with dexamethasone in the treatment of relapsed refractory multiple myeloma in adult patients with disease refractory to pomalidomide and/or an anti-CD38 monoclonal antibody. All patients in the study will be treated with melflufen on Day 1 and dexamethasone on Days 1, 8, 15 and 22 of each 28-day cycle.
NCT02963493 ↗ A Study of Melphalan Flufenamide (Melflufen) in Combination With Dexamethasone in Relapsed Refractory Multiple Myeloma Patients Active, not recruiting Precision Oncology Phase 2 2016-12-28 This study will evaluate melflufen in combination with dexamethasone in the treatment of relapsed refractory multiple myeloma in adult patients with disease refractory to pomalidomide and/or an anti-CD38 monoclonal antibody. All patients in the study will be treated with melflufen on Day 1 and dexamethasone on Days 1, 8, 15 and 22 of each 28-day cycle.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Melphalan Flufenamide Hydrochloride

Condition Name

Condition Name for Melphalan Flufenamide Hydrochloride
Intervention Trials
Multiple Myeloma 4
RRMM 2
AL Amyloidosis 1
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Condition MeSH

Condition MeSH for Melphalan Flufenamide Hydrochloride
Intervention Trials
Multiple Myeloma 5
Neoplasms, Plasma Cell 5
Immunoglobulin Light-chain Amyloidosis 1
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Clinical Trial Locations for Melphalan Flufenamide Hydrochloride

Trials by Country

Trials by Country for Melphalan Flufenamide Hydrochloride
Location Trials
United States 37
Czechia 6
Spain 5
Poland 5
France 4
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Trials by US State

Trials by US State for Melphalan Flufenamide Hydrochloride
Location Trials
Massachusetts 5
Ohio 4
California 4
New York 3
Florida 3
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Clinical Trial Progress for Melphalan Flufenamide Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Melphalan Flufenamide Hydrochloride
Clinical Trial Phase Trials
Phase 3 2
Phase 2 3
Phase 1/Phase 2 3
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Clinical Trial Status

Clinical Trial Status for Melphalan Flufenamide Hydrochloride
Clinical Trial Phase Trials
Active, not recruiting 7
Terminated 1
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Clinical Trial Sponsors for Melphalan Flufenamide Hydrochloride

Sponsor Name

Sponsor Name for Melphalan Flufenamide Hydrochloride
Sponsor Trials
Oncopeptides AB 8
Precision For Medicine 1
Precision Oncology 1
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Sponsor Type

Sponsor Type for Melphalan Flufenamide Hydrochloride
Sponsor Trials
Industry 10
Other 1
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