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Generated: December 16, 2018

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CLINICAL TRIALS PROFILE FOR MECHLORETHAMINE HYDROCHLORIDE

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Clinical Trials for Mechlorethamine Hydrochloride

Trial ID Title Status Sponsor Phase Summary
NCT00002462 RT or No RT Following Chemotherapy in Treating Patients With Stage III/IV Hodgkin's Disease Active, not recruiting European Organisation for Research and Treatment of Cancer - EORTC Phase 3 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy with combination chemotherapy may kill more tumor cells. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with no radiation therapy following chemotherapy in treating patients with stage III or stage IV Hodgkin's disease.
NCT00002463 Combination Chemotherapy in Treating Children With Astrocytomas and Primitive Neuroectodermal Tumors Completed National Cancer Institute (NCI) Phase 2 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of methotrexate, mechlorethamine, vincristine, procarbazine, and prednisone in treating children with astrocytomas or primitive neuroectodermal tumors.
NCT00002463 Combination Chemotherapy in Treating Children With Astrocytomas and Primitive Neuroectodermal Tumors Completed M.D. Anderson Cancer Center Phase 2 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of methotrexate, mechlorethamine, vincristine, procarbazine, and prednisone in treating children with astrocytomas or primitive neuroectodermal tumors.
NCT00002714 Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Early-Stage Hodgkin's Disease Completed National Cancer Institute (NCI) Phase 2 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining more than one chemotherapy drug with radiation therapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus radiation therapy in treating patients who have early stage Hodgkin's disease.
NCT00002714 Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Early-Stage Hodgkin's Disease Completed Stanford University Phase 2 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining more than one chemotherapy drug with radiation therapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus radiation therapy in treating patients who have early stage Hodgkin's disease.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Mechlorethamine Hydrochloride

Condition Name

Condition Name for Mechlorethamine Hydrochloride
Intervention Trials
Lymphoma 9
Mycosis Fungoides 4
Cutaneous T-cell Lymphoma 1
Brain and Central Nervous System Tumors 1
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Condition MeSH

Condition MeSH for Mechlorethamine Hydrochloride
Intervention Trials
Hodgkin Disease 11
Lymphoma 9
Mycosis Fungoides 4
Mycoses 4
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Clinical Trial Locations for Mechlorethamine Hydrochloride

Trials by Country

Trials by Country for Mechlorethamine Hydrochloride
Location Trials
United States 75
Canada 9
United Kingdom 4
Italy 3
France 1
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Trials by US State

Trials by US State for Mechlorethamine Hydrochloride
Location Trials
California 6
Texas 4
New York 4
Pennsylvania 4
Wisconsin 3
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Clinical Trial Progress for Mechlorethamine Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Mechlorethamine Hydrochloride
Clinical Trial Phase Trials
Phase 4 1
Phase 3 4
Phase 2 10
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Clinical Trial Status

Clinical Trial Status for Mechlorethamine Hydrochloride
Clinical Trial Phase Trials
Completed 6
Active, not recruiting 4
Unknown status 4
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Clinical Trial Sponsors for Mechlorethamine Hydrochloride

Sponsor Name

Sponsor Name for Mechlorethamine Hydrochloride
Sponsor Trials
National Cancer Institute (NCI) 5
Stanford University 2
Actelion 2
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Sponsor Type

Sponsor Type for Mechlorethamine Hydrochloride
Sponsor Trials
Other 16
NIH 6
Industry 5
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Serving hundreds of leading biopharmaceutical companies globally:

Johnson and Johnson
McKesson
Chinese Patent Office
Mallinckrodt
Cerilliant
Queensland Health
Teva
Boehringer Ingelheim
Merck

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