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Generated: February 19, 2019

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CLINICAL TRIALS PROFILE FOR MEBENDAZOLE

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Clinical Trials for Mebendazole

Trial ID Title Status Sponsor Phase Summary
NCT00116493 Severe Anemia Treatment Trials, Pakistan Completed Aga Khan University Phase 3 The purpose of this study is to test the efficacy of two enhanced regimens (deworming and multivitamins) in the treatment of severe anemia in pregnant women and children 6-24 months of age in Karachi, Pakistan.
NCT00116493 Severe Anemia Treatment Trials, Pakistan Completed Johns Hopkins Bloomberg School of Public Health Phase 3 The purpose of this study is to test the efficacy of two enhanced regimens (deworming and multivitamins) in the treatment of severe anemia in pregnant women and children 6-24 months of age in Karachi, Pakistan.
NCT01050452 Safety and Efficacy of Drug Combinations Against Trichuris Trichiura Completed DBL -Institute for Health Research and Development N/A This randomised, controlled, double-blinded clinical study investigates the safety and efficacy of albendazole (ALB), mebendazole (MBD) and ivermectin (IVM) separately, and ALB and MBD each in combination with IVM in the treatment of Trichuris trichiura in children aged 5-14 years.
NCT01173562 A Safety Study of Mebendazole in Children 2 to 10 Years of Age Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. Phase 3 The purpose of this study is to assess the safety and tolerability of mebendazole 500-mg chewable tablet formulation in a pediatric population. Mebendazole is a drug used for the treatment of soil-transmitted parasitic helminth (STH) (ie, parasitic worm) infections such as pinworm, whipworm, common roundworm, common hookworm, and American hookworm.
NCT01314937 The Effect of a Deworming Intervention to Improve Early Childhood Growth and Development in Resource-poor Areas Completed Asociacion Civil Selva Amazonica Phase 4 Worldwide, over 2 billion people suffer from worm infections in developing countries. These infections are especially damaging to the health of children, resulting in both short-term and lifelong disability. Older children with worm infections are more likely to be stunted, underweight, vulnerable to other illnesses and perform poorly in school compared to non-infected children. Large-scale deworming programs in school-age children are therefore recommended by the World Health Organization (WHO). WHO also recommends deworming of preschool-age children (as of 12 months of age) in these areas; however, the benefits of deworming, especially in the 12-24 month age group, have been inadequately studied. This knowledge is urgently needed as studies show that all children have a similar potential for healthy growth and development, provided that appropriate nutrition and health interventions are given in the critical window of opportunity before the age of two. Therefore, the investigators are proposing to undertake a randomized controlled trial to determine the effect of deworming program for improving growth and development in children between 12 and 24 months of age. Our results will provide solid rigorous evidence on if, when, and how often, deworming should be integrated into routine child health care packages provided by Ministries of Health in the 130 countries in the world where worm infections are endemic.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Mebendazole

Condition Name

Condition Name for Mebendazole
Intervention Trials
Helminthiasis 3
Anemia 2
Anaplastic Astrocytoma 2
Ascaris Lumbricoides 1
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Condition MeSH

Condition MeSH for Mebendazole
Intervention Trials
Infection 5
Communicable Diseases 5
Helminthiasis 5
Hookworm Infections 4
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Clinical Trial Locations for Mebendazole

Trials by Country

Trials by Country for Mebendazole
Location Trials
United States 3
Ethiopia 3
Tanzania 3
Uganda 2
Vietnam 1
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Trials by US State

Trials by US State for Mebendazole
Location Trials
Maryland 2
New York 1
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Clinical Trial Progress for Mebendazole

Clinical Trial Phase

Clinical Trial Phase for Mebendazole
Clinical Trial Phase Trials
Phase 4 9
Phase 3 5
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Mebendazole
Clinical Trial Phase Trials
Completed 14
Recruiting 5
Not yet recruiting 3
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Clinical Trial Sponsors for Mebendazole

Sponsor Name

Sponsor Name for Mebendazole
Sponsor Trials
Bill and Melinda Gates Foundation 3
University Ghent 3
Sidney Kimmel Comprehensive Cancer Center 2
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Sponsor Type

Sponsor Type for Mebendazole
Sponsor Trials
Other 60
Industry 7
NIH 1
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Serving hundreds of leading biopharmaceutical companies globally:

Covington
Citi
Mallinckrodt
Deloitte
McKesson
Dow
McKinsey
Chubb
Queensland Health

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