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Last Updated: April 25, 2024

CLINICAL TRIALS PROFILE FOR MAVENCLAD


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All Clinical Trials for Mavenclad

Trial ID Title Status Sponsor Phase Start Date Summary
NCT03150004 ↗ Efficacy and Pharmacogenomics of Salvage CLAG-M Chemotherapy in Patients With Relapse/Refractory and Secondary Acute Myeloid Leukemia Recruiting Medical College of Wisconsin Phase 2 2017-06-14 This is a prospective phase II clinical study to be conducted at the Medical College of Wisconsin. After meeting the study criteria and enrollment, patients will be treated with Cladribine, Cytarabine, Mitoxantrone, G-CSF (CLAG-M) chemotherapy and followed at periodic intervals to determine the primary and secondary objectives.
NCT03364036 ↗ Evaluation of the Onset of Action in Highly Active MS (MAGNIFY) Active, not recruiting Merck KGaA, Darmstadt, Germany Phase 4 2018-05-28 The main purpose of the study was to determine the onset of Mavenclad® action by frequent magnetic resonance imaging (MRI) assessment of the combined unique active (CUA) lesions in participants with highly active relapsing multiple sclerosis (MS).
NCT03369665 ↗ Evaluation of Quality of Life (QoL) in Subjects With Highly Active Relapsing Multiple Sclerosis (MS) (CLARIFY MS) Active, not recruiting Merck KGaA, Darmstadt, Germany Phase 4 2018-06-20 The main purpose of the study is to assess the health-related quality of life (HRQoL) through the Multiple Sclerosis Quality of Life-54 Questionnaire (MSQoL-54) scale in highly-active relapsing multiple sclerosis (RMS) subjects treated with Mavenclad® for 2 years (24 months).
NCT03441048 ↗ Lintuzumab-Ac225 in Combination With Cladribine + Cytarabine + Filgastrim + Mitoxantrone (CLAG-M) for Relapsed/Refractory Acute Myeloid Leukemia Recruiting Medical College of Wisconsin Phase 1 2018-05-22 This is a prospective, single-center phase I clinical study aimed at determining the maximum-tolerated dose and safety of Lintuzumab-Ac225 in combination with CLAG-M chemotherapy in the management of relapsed/refractory acute myeloid leukemia. This study uses a 3+3 design to estimate the maximum-tolerated dose (MTD).
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Mavenclad

Condition Name

Condition Name for Mavenclad
Intervention Trials
Multiple Sclerosis 7
Acute Myeloid Leukemia 2
Relapsing Multiple Sclerosis 1
Advanced Multiple Sclerosis 1
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Condition MeSH

Condition MeSH for Mavenclad
Intervention Trials
Multiple Sclerosis 9
Sclerosis 8
Leukemia, Myeloid 2
Leukemia 2
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Clinical Trial Locations for Mavenclad

Trials by Country

Trials by Country for Mavenclad
Location Trials
Norway 11
France 5
Spain 5
Poland 5
United Kingdom 5
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Trials by US State

Trials by US State for Mavenclad
Location Trials
Wisconsin 2
New York 1
Texas 1
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Clinical Trial Progress for Mavenclad

Clinical Trial Phase

Clinical Trial Phase for Mavenclad
Clinical Trial Phase Trials
Phase 4 7
Phase 3 1
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Mavenclad
Clinical Trial Phase Trials
Recruiting 7
Active, not recruiting 3
Not yet recruiting 1
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Clinical Trial Sponsors for Mavenclad

Sponsor Name

Sponsor Name for Mavenclad
Sponsor Trials
Medical College of Wisconsin 2
Merck KGaA, Darmstadt, Germany 2
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 2
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Sponsor Type

Sponsor Type for Mavenclad
Sponsor Trials
Other 25
Industry 6
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