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Generated: December 13, 2018

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CLINICAL TRIALS PROFILE FOR MARQIBO KIT

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Clinical Trials for Marqibo Kit

Trial ID Title Status Sponsor Phase Summary
NCT00025259 Chemotherapy With or Without Additional Chemotherapy and/or Radiation Therapy in Treating Children With Newly Diagnosed Hodgkin's Disease Completed National Cancer Institute (NCI) Phase 3 This randomized phase III trial is studying different chemotherapy regimens given with or without radiation therapy to compare how well they work in treating children with newly diagnosed Hodgkin's disease. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Giving the drugs in different combinations may kill more cancer cells. Radiation therapy uses high-energy x-rays to damage cancer cells. It is not yet known if chemotherapy is more effective with or without additional chemotherapy and/or radiation therapy in treating Hodgkin's disease.
NCT00025259 Chemotherapy With or Without Additional Chemotherapy and/or Radiation Therapy in Treating Children With Newly Diagnosed Hodgkin's Disease Completed Children's Oncology Group Phase 3 This randomized phase III trial is studying different chemotherapy regimens given with or without radiation therapy to compare how well they work in treating children with newly diagnosed Hodgkin's disease. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Giving the drugs in different combinations may kill more cancer cells. Radiation therapy uses high-energy x-rays to damage cancer cells. It is not yet known if chemotherapy is more effective with or without additional chemotherapy and/or radiation therapy in treating Hodgkin's disease.
NCT00072384 Systemic Vincristine, Carboplatin, and Etoposide, Subtenon Carboplatin, and Local Ophthalmic Therapy in Treating Children With Intraocular Retinoblastoma Completed National Cancer Institute (NCI) Phase 3 Phase III trial to determine the effectiveness of combining systemic chemotherapy and subtenon carboplatin with ophthalmic therapy in treating children who have intraocular retinoblastoma. Drugs used in chemotherapy, such as vincristine, carboplatin, and etoposide, work in different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether systemic chemotherapy and subtenon (under the conjunctiva of the eye) carboplatin combined with ophthalmic therapy is effective in treating intraocular (within the eyeball) retinoblastoma.
NCT00072384 Systemic Vincristine, Carboplatin, and Etoposide, Subtenon Carboplatin, and Local Ophthalmic Therapy in Treating Children With Intraocular Retinoblastoma Completed Children's Oncology Group Phase 3 Phase III trial to determine the effectiveness of combining systemic chemotherapy and subtenon carboplatin with ophthalmic therapy in treating children who have intraocular retinoblastoma. Drugs used in chemotherapy, such as vincristine, carboplatin, and etoposide, work in different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether systemic chemotherapy and subtenon (under the conjunctiva of the eye) carboplatin combined with ophthalmic therapy is effective in treating intraocular (within the eyeball) retinoblastoma.
NCT00144963 Liposomal Vincristine Plus Dexamethasone in Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia Completed Spectrum Pharmaceuticals, Inc Phase 1/Phase 2 The purpose of this study is to find the highest safe dose and to assess the anti-tumor effect of liposomal vincristine with dexamethasone in patients with relapsed or refractory acute lymphoblastic leukemia (ALL).
NCT00145041 Pharmacokinetic Study of Liposomal Vincristine in Patients With Malignant Melanoma & Hepatic Dysfunction Completed Spectrum Pharmaceuticals, Inc Phase 1 The purpose of this study is to see how vincristine, when placed in an oil droplet called a liposome (VSLI), is absorbed, distributed (moved around) and excreted from the the body (pharmacokinetics). This study will also assess the safety of VSLI and to see if VSLI will slow the growth or shrink tumors in patients with metastatic melanoma that has resulted in liver impairment, and who have relapsed after previous therapies.
NCT00335738 Vincristine, Carboplatin, and Etoposide or Observation Only in Treating Patients Who Have Undergone Surgery for Newly Diagnosed Retinoblastoma Completed National Cancer Institute (NCI) Phase 3 This phase III trial is studying vincristine, carboplatin, and etoposide to see how well they work compared to observation only in treating patients who have undergone surgery for newly diagnosed retinoblastoma. Drugs used in chemotherapy, such as vincristine, carboplatin, and etoposide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) after surgery may kill any tumor cells that remain after surgery. Sometimes, after surgery, no additional treatment is needed for the tumor until it progresses. In this case, observation may be sufficient.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Marqibo Kit

Condition Name

Condition Name for Marqibo Kit
Intervention Trials
Acute Lymphoblastic Leukemia (ALL) 2
Acute Lymphoblastic Leukemia 2
Recurrent Adult Acute Lymphoblastic Leukemia 2
Stage III Childhood Hodgkin Lymphoma 2
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Condition MeSH

Condition MeSH for Marqibo Kit
Intervention Trials
Leukemia 10
Precursor Cell Lymphoblastic Leukemia-Lymphoma 9
Leukemia, Lymphoid 9
Lymphoma 7
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Clinical Trial Locations for Marqibo Kit

Trials by Country

Trials by Country for Marqibo Kit
Location Trials
United States 423
Canada 61
Australia 31
New Zealand 8
Puerto Rico 5
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Trials by US State

Trials by US State for Marqibo Kit
Location Trials
Texas 18
California 16
Illinois 14
Georgia 12
Pennsylvania 12
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Clinical Trial Progress for Marqibo Kit

Clinical Trial Phase

Clinical Trial Phase for Marqibo Kit
Clinical Trial Phase Trials
Phase 3 8
Phase 2 7
Phase 1/Phase 2 3
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Clinical Trial Status

Clinical Trial Status for Marqibo Kit
Clinical Trial Phase Trials
Completed 10
Recruiting 4
Active, not recruiting 3
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Clinical Trial Sponsors for Marqibo Kit

Sponsor Name

Sponsor Name for Marqibo Kit
Sponsor Trials
National Cancer Institute (NCI) 13
Spectrum Pharmaceuticals, Inc 11
Children's Oncology Group 7
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Sponsor Type

Sponsor Type for Marqibo Kit
Sponsor Trials
Other 16
NIH 13
Industry 12
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Serving hundreds of leading biopharmaceutical companies globally:

Express Scripts
Dow
Daiichi Sankyo
UBS
Moodys
Argus Health
Merck
Harvard Business School
Accenture

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