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Last Updated: January 26, 2023

CLINICAL TRIALS PROFILE FOR MARCAINE


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All Clinical Trials for Marcaine

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00180687 ↗ Clinical Trial of the Use of Intraperitoneal Local Anaesthetic Completed Imperial College London Phase 3 2004-10-01 Patients undergoing keyhole gall bladder removal will be divided into 3 groups, one control, one will have local anaesthetic and the third will have normal saline nebulised into their abdomen before closure of the wounds to reduce postoperative pain. These medications will be given on top of the standard pain management protocol.
NCT00472134 ↗ Laparoscopic Ventral Hernia Repair With Elastomeric Pain Pump Completed University Hospitals Cleveland Medical Center N/A 2005-12-01 The purpose of this study is to determine the effects of a local anesthetic dispensed via a tiny catheter device, called the ON-Q PainBuster pump, placed during surgery on top of the mesh used in the laparoscopic repair of ventral hernias. The goals are: - reducing postoperative pain from this procedure - decreasing length of hospital stay - reducing or eliminating amount of post-operative narcotics used
NCT00508066 ↗ Continuous Local Infusion of Anesthetic at the Incisional Site for Scoliosis Surgery Completed Shriners Hospitals for Children Phase 4 2007-05-01 The purpose of this study is to evaluate the effects of continuous local anesthetic delivery on the immediate post-op recovery of patients undergoing spinal fusion surgery for congenital or idiopathic scoliosis.
NCT00508976 ↗ Clinical Proposal for the Comparison of Intraperitoneal Anesthetic to Injected Local Anesthetic Completed Pinnacle Health System Phase 2 2007-06-01 The purpose of this study is to determine if pre-incisional lidocaine injection, instilled liquid bupivacaine, intra-abdominal aerosolized bupivacaine, or post-operative bupivacaine injection is superior in post-operative pain control in laparoscopic bariatric surgical patients.
NCT00532662 ↗ Postoperative Analgesia by Epidural vs IV Ketamine Concurrent With Caudal Anesthesia in Pediatric Orthopedic Surgery Unknown status Tehran University of Medical Sciences Phase 4 2007-11-01 Preemptive analgesia can improve postoperative pain management. Ketamine may prevent central sensitization during surgery and result in preemptive analgesia. The purpose of this study is to examine the effectiveness of ketamine as a preemptive analgesic as previous studies have shown the involvement of N-methyl-D-Aspartate (NMDA) receptor in neuroplasticity.
NCT00533845 ↗ Intraperitoneal Bupivicaine Infusion Using the On-Q Pain Pump After Laparoscopic Surgery Completed Maimonides Medical Center Phase 4 2007-09-01 After Laparoscopic surgery most patients experience some form of mild to moderate pain. The current standard of care is to treat this pain with local anesthetics (numbing medication, that deadens the nerve endings) to the small surgical incisions (cuts) and narcotic systemic analgesics (medication injected into your vein to control pain such as morphine). Although this treatment improves pain symptoms it is not perfect. Firstly, complete pain control is rarely achieved and secondly, narcotics (such as morphine) often have many side effects including nausea, vomiting, sedation (sleepiness), constipation and abdominal upset. All of these issues make recovery less comfortable and delays return to full function (work, school and other activities of daily life). A new FDA approved device is now available that offers the benefits of long term anesthesia without the side effects of narcotics. It consists of a pump that continuously infuses local anesthesia into and around the surgical site. This pump is placed during your operation. You then carry a tennis ball sized container made of soft plastic in a pouch which drips numbing medicine around your wounds for 2 days continuously. The purpose of this study is to see if this pump improves postoperative pain, decreases the need for narcotic pain medicine and allows people to return to their activities earlier.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Marcaine

Condition Name

Condition Name for Marcaine
Intervention Trials
Pain, Postoperative 36
Postoperative Pain 26
Pain 26
Anesthesia, Local 10
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Condition MeSH

Condition MeSH for Marcaine
Intervention Trials
Pain, Postoperative 90
Fractures, Bone 9
Hernia, Inguinal 8
Hernia 8
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Clinical Trial Locations for Marcaine

Trials by Country

Trials by Country for Marcaine
Location Trials
United States 156
Egypt 35
Turkey 18
Canada 16
Israel 6
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Trials by US State

Trials by US State for Marcaine
Location Trials
California 20
New York 15
Illinois 12
Ohio 10
Pennsylvania 10
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Clinical Trial Progress for Marcaine

Clinical Trial Phase

Clinical Trial Phase for Marcaine
Clinical Trial Phase Trials
Phase 4 105
Phase 3 24
Phase 2/Phase 3 3
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Clinical Trial Status

Clinical Trial Status for Marcaine
Clinical Trial Phase Trials
Completed 139
Recruiting 45
Unknown status 32
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Clinical Trial Sponsors for Marcaine

Sponsor Name

Sponsor Name for Marcaine
Sponsor Trials
Cairo University 11
Istanbul University 11
Assiut University 7
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Sponsor Type

Sponsor Type for Marcaine
Sponsor Trials
Other 325
Industry 17
U.S. Fed 2
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