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Last Updated: May 21, 2022

CLINICAL TRIALS PROFILE FOR MALARONE


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All Clinical Trials for Malarone

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00298610 ↗ Safety and Efficacy Study of IV Artesunate to Treat Malaria Completed Military Infectious Diseases Research Program (MIDRP) Phase 2 2006-03-01 The purpose of this study is to determine how GMP IV Artesunate is metabolized and cleared by individuals with uncomplicated malaria infection and to determine how fast it eliminates malaria infection from the body.
NCT00298610 ↗ Safety and Efficacy Study of IV Artesunate to Treat Malaria Completed U.S. Army Medical Research and Development Command Phase 2 2006-03-01 The purpose of this study is to determine how GMP IV Artesunate is metabolized and cleared by individuals with uncomplicated malaria infection and to determine how fast it eliminates malaria infection from the body.
NCT00298610 ↗ Safety and Efficacy Study of IV Artesunate to Treat Malaria Completed U.S. Army Office of the Surgeon General Phase 2 2006-03-01 The purpose of this study is to determine how GMP IV Artesunate is metabolized and cleared by individuals with uncomplicated malaria infection and to determine how fast it eliminates malaria infection from the body.
NCT00421473 ↗ Drug Interaction Study Between Atovaquone and Antiretroviral Agents in HIV-1 Infected Patients Completed Radboud University Phase 4 2007-03-01 Malarone┬« (atovaquone/proguanil) is frequently used in malaria prophylaxis. Unfortunately, there are indications that certain anti-HIV agents may decrease atovaquone plasma levels by induction of atovaquone metabolism. For travelling HIV patients, the clinical consequences of these possible drug drug interactions are serious, since a diminished exposure to the anti-malarial drug will result in suboptimal prophylaxis of malaria and potential development of drug resistant strains of Plasmodium falciparum. The purpose of this study is to find out if HIV patients using HAART regimes with either lopinavir/ritonavir, atazanavir/ritonavir or efavirenz have lower atovaquone plasma levels than healthy volunteers after a single dose of atovaquone/proguanil.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Malarone

Condition Name

Condition Name for Malarone
Intervention Trials
Malaria 13
Malaria,Falciparum 2
PCP 1
Falciparum 1
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Condition MeSH

Condition MeSH for Malarone
Intervention Trials
Malaria 16
Malaria, Falciparum 3
Infections 2
Infection 2
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Clinical Trial Locations for Malarone

Trials by Country

Trials by Country for Malarone
Location Trials
Netherlands 8
United States 7
Colombia 1
Germany 1
Vietnam 1
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Trials by US State

Trials by US State for Malarone
Location Trials
Maryland 5
New York 1
Washington 1
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Clinical Trial Progress for Malarone

Clinical Trial Phase

Clinical Trial Phase for Malarone
Clinical Trial Phase Trials
Phase 4 6
Phase 2 3
Phase 1/Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Malarone
Clinical Trial Phase Trials
Completed 18
Withdrawn 2
Not yet recruiting 2
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Clinical Trial Sponsors for Malarone

Sponsor Name

Sponsor Name for Malarone
Sponsor Trials
Radboud University 6
U.S. Army Medical Research and Development Command 3
Medicines for Malaria Venture 3
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Sponsor Type

Sponsor Type for Malarone
Sponsor Trials
Other 35
U.S. Fed 9
Industry 5
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