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CLINICAL TRIALS PROFILE FOR MAGNESIUM SULFATE

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Clinical Trials for Magnesium Sulfate

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00002146	Safety and Efficacy of Intravenous Magnesium Sulfate in Modulating Changes in Symptoms and Divalent Cation Levels Associated With Foscavir Therapy: A Phase IV Randomized, Double-Blind, Placebo-Controlled, Cross-Over, Pilot Study	Completed	Astra USA	Phase 4	To determine whether acute ionized hypomagnesemia and hypocalcemia immediately following foscarnet infusions can be lessened or eliminated by prior infusion of magnesium sulfate. To determine whether reductions in ionized magnesium, ionized calcium, and parathyroid hormone levels following foscarnet infusions are lessened by preinfusion of magnesium sulfate. To evaluate the safety of intravenous magnesium sulfate prior to foscarnet infusion by monitoring blood pressure, heart rate, and heart rhythm. To characterize the effect of magnesium sulfate on foscarnet blood levels and urinary excretion of calcium, magnesium, phosphate, and foscarnet.
NCT00004399	Randomized Study of Nimodipine Versus Magnesium Sulfate in the Prevention of Eclamptic Seizures in Patients With Severe Preeclampsia	Completed	University of Utah	N/A	OBJECTIVES: I. Determine the effectiveness of nimodipine versus magnesium sulfate in the prevention of eclamptic seizures in patients with severe preeclampsia.
NCT00004399	Randomized Study of Nimodipine Versus Magnesium Sulfate in the Prevention of Eclamptic Seizures in Patients With Severe Preeclampsia	Completed	FDA Office of Orphan Products Development	N/A	OBJECTIVES: I. Determine the effectiveness of nimodipine versus magnesium sulfate in the prevention of eclamptic seizures in patients with severe preeclampsia.
NCT00004730	Magnesium Sulfate For Brain Injury	Completed	University of Washington	Phase 3	The purpose of the study is to determine whether magnesium sulfate, given within 8 hours of a moderate or severe traumatic brain injury improves survival, decreases the number of people developing seizures, improves the survivors' mental and psychological functioning, including the ability to return to daily life, live independently, and return to work or school.

Clinical Trial Conditions for Magnesium Sulfate

Condition Name

Condition Name for Magnesium Sulfate
Intervention	Trials
Postoperative Pain	9
Preeclampsia	8
Asthma	8
Pain	6

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Condition MeSH

Condition MeSH for Magnesium Sulfate
Intervention	Trials
Pre-Eclampsia	18
Pain, Postoperative	15
Obstetric Labor, Premature	11
Asthma	11

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Clinical Trial Locations for Magnesium Sulfate

Trials by Country

Trials by Country for Magnesium Sulfate
Location	Trials
United States	107
Egypt	28
Canada	11
Brazil	9
Korea, Republic of	8

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Trials by US State

Trials by US State for Magnesium Sulfate
Location	Trials
New York	8
Ohio	7
California	7
Pennsylvania	6
Illinois	6

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Clinical Trial Progress for Magnesium Sulfate

Clinical Trial Phase

Clinical Trial Phase for Magnesium Sulfate
Clinical Trial Phase	Trials
Phase 4	36
Phase 3	26
Phase 2/Phase 3	13

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Clinical Trial Status

Clinical Trial Status for Magnesium Sulfate
Clinical Trial Phase	Trials
Completed	68
Recruiting	34
Not yet recruiting	22

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Clinical Trial Sponsors for Magnesium Sulfate

Sponsor Name

Sponsor Name for Magnesium Sulfate
Sponsor	Trials
Assiut University	17
Cairo University	8
Seoul National University Bundang Hospital	5

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Sponsor Type

Sponsor Type for Magnesium Sulfate
Sponsor	Trials
Other	188
NIH	10
Industry	9

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