Impact of Lofexidine on Stress, Craving and Opioid Use
Recruiting
National Institute on Drug Abuse (NIDA)
Phase 2
2019-06-26
Individuals with opioid use disorder who are stabilized on buprenorphine or methadone will be
randomly assigned to receive placebo or lofexidine for 5 weeks. At the end of five weeks,
they will complete a human laboratory stress task and scripted opioid imagery task.
Throughout the study a CREMA app (Cue Reactivity Ecological Momentary Assessment) will be
used to monitor stress, craving and use in the natural environment.
Impact of Lofexidine on Stress, Craving and Opioid Use
Recruiting
National Institutes of Health (NIH)
Phase 2
2019-06-26
Individuals with opioid use disorder who are stabilized on buprenorphine or methadone will be
randomly assigned to receive placebo or lofexidine for 5 weeks. At the end of five weeks,
they will complete a human laboratory stress task and scripted opioid imagery task.
Throughout the study a CREMA app (Cue Reactivity Ecological Momentary Assessment) will be
used to monitor stress, craving and use in the natural environment.
Impact of Lofexidine on Stress, Craving and Opioid Use
Recruiting
Medical University of South Carolina
Phase 2
2019-06-26
Individuals with opioid use disorder who are stabilized on buprenorphine or methadone will be
randomly assigned to receive placebo or lofexidine for 5 weeks. At the end of five weeks,
they will complete a human laboratory stress task and scripted opioid imagery task.
Throughout the study a CREMA app (Cue Reactivity Ecological Momentary Assessment) will be
used to monitor stress, craving and use in the natural environment.
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