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Last Updated: November 19, 2019

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CLINICAL TRIALS PROFILE FOR LOVASTATIN

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505(b)(2) Clinical Trials for Lovastatin

This table shows clinical trials for potential 505(b)(2) applications. See the next table for all clinical trials
Trial Type Trial ID Title Status Sponsor Phase Start Date Summary
OTC NCT00092846 A 6-Month Consumer Behavior Study of a Self-Management System (0803-084)(COMPLETED) Completed Merck Sharp & Dohme Corp. Phase 3 2002-12-01 The purpose of this study is to evaluate the ability of patients with intermediate risk of heart disease to appropriately use a Self-Management System.
>Trial Type >Trial ID >Title >Status >Phase >Start Date >Summary

All Clinical Trials for Lovastatin

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000463 Post Coronary Artery Bypass Graft (CABG) Study Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 1987-04-01 To determine the relative effectiveness of moderate versus more aggressive lipid lowering, and of low dose anticoagulation versus placebo, in delaying saphenous vein coronary bypass graft atherosclerosis and preventing occlusion of saphenous grafts of patients with saphenous vein coronary bypass grafts placed 1 to 11 years previously.
NCT00000469 Asymptomatic Carotid Artery Plaque Study (ACAPS) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 2 1988-05-01 To determine whether warfarin or lovastatin alone or in combination retarded the progression of atherosclerotic plaques in the carotid arteries of high risk individuals with asymptomatic carotid stenosis. Also, to determine if a full scale trial was feasible.
NCT00000477 Cholesterol Reduction in Seniors Program (CRISP) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 2 1990-07-01 To conduct a pilot study to determine whether lowering elevated serum cholesterol levels with 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG CoA) reductase inhibitors reduced mortality due to the sequelae of atherosclerotic cardiovascular disease in older men and women.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Lovastatin

Condition Name

Condition Name for Lovastatin
Intervention Trials
Hypercholesterolemia 6
Cardiovascular Diseases 5
Heart Diseases 4
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Condition MeSH

Condition MeSH for Lovastatin
Intervention Trials
Hypercholesterolemia 8
Cardiovascular Diseases 7
Syndrome 5
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Clinical Trial Locations for Lovastatin

Trials by Country

Trials by Country for Lovastatin
Location Trials
United States 116
Canada 11
Taiwan 7
Germany 3
Korea, Republic of 3
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Trials by US State

Trials by US State for Lovastatin
Location Trials
California 15
Pennsylvania 6
New York 6
Utah 5
North Carolina 5
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Clinical Trial Progress for Lovastatin

Clinical Trial Phase

Clinical Trial Phase for Lovastatin
Clinical Trial Phase Trials
Phase 4 10
Phase 3 10
Phase 2/Phase 3 2
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Clinical Trial Status

Clinical Trial Status for Lovastatin
Clinical Trial Phase Trials
Completed 39
Recruiting 11
Terminated 4
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Clinical Trial Sponsors for Lovastatin

Sponsor Name

Sponsor Name for Lovastatin
Sponsor Trials
National Heart, Lung, and Blood Institute (NHLBI) 5
National Taiwan University Hospital 4
National Science Council, Taiwan 3
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Sponsor Type

Sponsor Type for Lovastatin
Sponsor Trials
Other 73
Industry 23
NIH 14
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