The objective of this study is to determine if a subject's genetic make-up would affect the
treatment response to codeine in subjects with sickle cell disease.
Low-Dose Opiate Therapy for Discomfort in Dementia (L-DOT)
Completed
VA Office of Research and Development
Phase 4
2007-10-01
The purpose of this study was to determine whether a low dose an opiate pain medication is
effective for the treatment of discomfort in patients with advanced dementia. The study
medication was also known as Lortab and contained both a narcotic pain medication and
acetaminophen (the same pain medication as contained in Tylenol). This study was an
eight-week long clinical trial for discomfort among veterans with advanced dementia who were
admitted to a Nursing Home Care Unit (NHCU) at the Tuscaloosa VA Medical Center.
The Comparison of Supraperiosteal Nerve Block With Opiate Analgesia in Alleviating the Pain of Toothache
Completed
Albany Medical College
Phase 4
2007-12-01
This study will compare the degree of pain control provided by two techniques for persons
with toothache in an emergency department. The two techniques include;
- standard oral narcotic pain medication
- numbing the tooth with local anesthetic by needle injection
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