Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Phase 4
2003-02-01
Irregular or prolonged menstrual bleeding and/or spotting are common side effects in patients
using progestin-only hormonal contraception such as levonorgestrel implants (Norplant).
Doxycycline, a drug approved by the Food and Drug Administration (FDA) to treat gum disease,
may reduce the occurrence of uterine bleeding and spotting in women who use Norplant. This
study will evaluate the effects of doxycycline on uterine bleeding/spotting in women using
Norplant.
A Study to Evaluate Suppression of the Pituitary-Ovarian Axis With Three Different Oral Contraceptive Regimens
Completed
Duramed Research
Phase 3
2005-06-01
This is a randomized, open-label study to evaluate pituitary ovarian suppression in healthy,
reproductive-aged women using three different regimens of oral contraceptives (OCs). Two
extended regimen OCs, Seasonale (levonorgestrel/ethinyl estradiol 0.15/0.03 mg for 84 days
followed by 7 days of placebo), and Seasonique (levonorgestrel/ethinyl estradiol 0.15/0.03 mg
for 84 days followed by 7 days of ethinyl estradiol 0.01 mg), and a 28-day regimen OC, Portia
(levonorgestrel/ethinyl estradiol 0.15/0.03 mg for 21 days followed by 7 days of placebo).
Study Evaluating Combination of Levonorgestrel (LNG) and Ethinyl Estradiol (EE) in Premenstrual Dysphoric Disorder
Completed
Wyeth is now a wholly owned subsidiary of Pfizer
Phase 3
2005-08-01
The purpose of this study is to determine whether levonorgestrel (LNG)/ethinyl estradiol (EE)
is effective in treating the symptoms of severe premenstrual syndrome (PMS).
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